Viral sepsis: diagnosis, clinical features, pathogenesis, and clinical considerations

Ji-Qian Xu; Wan-Ying Zhang; Jia-Ji Fu; Xiang-Zhi Fang; Cheng-Gang Gao; Chang Li; Lu Yao; Qi-Lan Li; Xiao-Bo Yang; Le-Hao Ren; Hua-Qing Shu; Ke Peng; Ying Wu; Ding-Yu Zhang; Yang Qiu; Xi Zhou; Yong-Ming Yao; You Shang

doi:10.1186/s40779-024-00581-0

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Viral sepsis: diagnosis, clinical features, pathogenesis, and clinical considerations

REVIEW | Updated：2025-12-13

- Viral sepsis: diagnosis, clinical features, pathogenesis, and clinical considerations
- Viral sepsis: diagnosis, clinical features, pathogenesis, and clinical considerations
- “本综述报告了脓毒症领域的最新研究，阐明了病毒性脓毒症的定义和诊断标准，综合了目前关于其病因、流行病学和病理生理学、其中涉及的分子机制及其对免疫介导器官损伤的影响的知识。关于现有疗法和先进治疗干预措施的专家讨论旨在加强对病毒性败血症的全面了解。”
- Military Medical Research 2025年12卷第9期页码：1387-1415
- Affiliations：
  
  1.Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
  2.State Key Laboratory of Virology, Center for Antiviral Research, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 43007, China
  3.State Key Laboratory of Virology and Hubei Province Key Laboratory of Allergy and Immunology, Institute of Medical Virology, TaiKang Medical School, Wuhan University, Wuhan 430072, China
  4.Translational Medicine Research Center, Medical Innovation Research Division and the Fourth Medical Center of Chinese, PLA General Hospital, Beijing 100853, China
- Author bio：
  
  * Xi Zhou zhouxi@wh.iov.cn
  Yong-Ming Yao c_ff@sina.com
  You Shang you_shang@hust.edu.cn
- Funds：
  
  the National Natural Science Foundation of China(82372176;82272217;82002026;81971818);the Hubei Provincial Key Research and Development Program of China(2023BCB091);the National Key Research and Development Program of China(2021YFC2500802;2021YFC2300200)
- DOI：10.1186/s40779-024-00581-0
  中图分类号：
- 收稿：2024-03-04，
  
  录用：2024-11-08，
  
  网络首发：2024-12-16，
  
  纸质出版：2025-09
- Accepted：
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Ji-Qian Xu, Wan-Ying Zhang, Jia-Ji Fu, 等. Viral sepsis: diagnosis, clinical features, pathogenesis, and clinical considerations[J]. Military Medical Research, 2025,12(9):1387-1415.

Ji-Qian Xu, Wan-Ying Zhang, Jia-Ji Fu, et al. Viral sepsis: diagnosis, clinical features, pathogenesis, and clinical considerations[J]. Military Medical Research, 2025, 12(9): 1387-1415.
Ji-Qian Xu, Wan-Ying Zhang, Jia-Ji Fu, 等. Viral sepsis: diagnosis, clinical features, pathogenesis, and clinical considerations[J]. Military Medical Research, 2025,12(9):1387-1415. DOI： 10.1186/s40779-024-00581-0.

Ji-Qian Xu, Wan-Ying Zhang, Jia-Ji Fu, et al. Viral sepsis: diagnosis, clinical features, pathogenesis, and clinical considerations[J]. Military Medical Research, 2025, 12(9): 1387-1415. DOI： 10.1186/s40779-024-00581-0.

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Viral sepsis: diagnosis, clinical features, pathogenesis, and clinical considerations

Viral sepsis: diagnosis, clinical features, pathogenesis, and clinical considerations

DOI：10.1186/s40779-024-00581-0