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Volume ， Issue 3 ， 1990
- Abstract：<正> Thirty adult upper extremities were used to study the arteries of the hand byangiography,cross-sectional dissection and three-dimensional reconstruction withmicrocomputer.The arterial skeleton of the palm was composed of superficial,deep anddorsal planes.There were three main anastomotic pathways between the radial and ulnararteries or their branches in the radio-ulnar direction,while in the palmar dorsal dirce-tion there were three anastomotic zones between the palrnar and dorsal arterial plancs.The branches of the deep palmar arch radiated distally,proximally,palmarly anddorsally,so that the arch acted as the center of the arterial network of the hand.Thetransverse arterial allocations in the carpo-metacarpal segment of the palm were four intypes,but in the mid-palmar and metacarpo-phalangcal segments were three only.Accord-ing to the sources,cross-sectional area,irrigation territories and anastomoses of the ar-teries in each segment,the clinical significance in the rcplantation of the amputatcd palmshas been discussed0|12|0Updated：2026-03-12
- Abstract：<正> The electron microscopic topology of Con A and WGA receptors was investi-gated in human peritoneal macrophagcs by utilizing avidin-gold colloids.Our observa-tions confirmed that both the receptors were distributed on the cell membranes,yet thereceptor expression showed variations among the individual cells.Some cells had abun-dant receptors,while others had only few receptors.The data obtained in the presentstudy indicate that human peritoneal macrophages may be a functionally andbiochemically heterogenous population,and the study may also serve as a theorcticalreference for future clinical exploitation of human peritoneal macrophages.0|3|0Updated：2026-03-12
- Abstract：<正> Photocarcinorin was prepared in our Lab and its composition was differentfrom that of any other hematoporphyrin photosensitizers by TLC and HPLC analyses.The 95% fiducial limits of iv LD in mice were 176-236 mg·kg-1.The iv MLD indogs was 171 mg·kg-1.The acute and subacutc toxic tests in 37 dogs showed that theintoxicated manifestations were characterized by a complex syndrome always seen inporphyrias.The biological,laboratory and histopathologic findings revealed that theliver,kidney and erythroeytic series were the target organs.The damages were dose-related and reversible within 2 wk.he phototoxicity was determined in mice with UV ra-diation and compared with that of HpD.The extent of its phototoxic reactions waslower than that of HpD’s.0|11|0Updated：2026-03-12
- Abstract：<正> The results of visual event-related potential（ERP）examinations and reactiontime（RT）tests were reported in 30 elders and compared with their performanceintellegence quotient（PIQ）scores.The subjects consisted of 18 males and 12 femalesaged 50-71（mean 61.4）years old.No history of central nervous system disease wasfound.The visual stimuli were randomly presented to the subject,including three sym-bols:E as target stimulus with 0.15 probability,and H and E as nontarget stimuliwith 0.15 and 0.70 probability respectively.The recording electrodes were placed on Fzand Pz.The duration from the subject seeing the target to touching a button immediatelywas considered as reaction time（RT）.It was shown that the P3 latency at Pz was longer than that at Fz and the P3amplitude at Pz was larger than that at Fz,and that the RT was longer than P3 latencywith obvious effect of distribution（P<0.05 at Fz and P>0.05 at Pz）as well .The higherthe PIQ scores,the longer the RT and the P3 latency.It is suggested that the ERPmight reflect the differences of PIQ scores,and the P3 is an objective index.We considerthat the research of ERP is of great interest in the neuropsychological and neurological sci-ences.0|25|0Updated：2026-03-12
- Abstract：<正> Radioimmunoassay was employed to dctermine the immunorcactivc met-enkephalin（ir-MEK）contents of several brain regions .The pain threshold（PT）andir-MEK content of striatum and hypothalamus increased markedly afterintraoerebroventricular injection of substance P（SP）in the dosage of lμgg/10μl ,but nosignificant change of ir-MEK content in hippocampus was observed.When theperiaqueductal gray（PAG）was destroyed with electrolysis,the increase of PT andir-MEK content in the two brain regions after SP injection was obviouslysuppressed（P<0.05-0.01）.The PT and ir-MEK content of hypothalamus andstriatum would also increase after intra-PAG injection of SP（0.4μg/4μl）,electroacupuncture or intraperitoneal injection of morphine.The ir-MEK content ofhippocampus could also increase after intra-PAG injection of SP or intraperitoncal injec-tion of morphine.The combination of intra-PAG injection of SP andelectroacupuncture caused a more marked elevation of PT and ir-MEK content of the 3brain regions than either of the two used singly could（P<0.01 ）.The combined effect ofintra-PAG injection of SP and intraperitoneal injection of morphine was similar to thatof either of the two used singly（P>0.05）.These facts indicate that thc analgesic effect ofSP activated by PAG was mediated through the increase of cerebral met-cnkcphalin con-tent,and there was a synergic effect between SP and elcctroacupuncturc.0|7|0Updated：2026-03-12
- Abstract：<正> In order to provide an experimental foundation and pathological base for earlyreconstruction of maxillofacial tissues defects after firearms wound using microsurgicalmethods,an experiment,was made to study the microvascular pathological changesthrough light and electron microscopy observation.In the experiment we found somepathological changes of small vessels in wounded region,such as mierothrombi forma-tion,endothelial loss,internal elastic membrane break and some degenerations,necrosis within endothelial and smooth muscle cells of vessel.The nearer the woundededge was,the more evident injury was.The microvascular injurous range was 3 cm dis-tant from wounded edge,which recovered in 7 days later after wounding.The experi-ment indicated that if we used the vascularized free tissue transfer to repair defects ofmaxillofacial firearms wounds,the pedicles of flap should be anastomosed to distant re-cipient vesseles which could be chosen beyond 3 cm from wounded edge.Thereconstructive operation should be done 7 days later after wound.0|3|0Updated：2026-03-12
- Abstract：<正> The expression of blood type Yantigen in the epithelial cells from 46cases of breast adenosis,5 cases of malig-nant degeneration of adenosis,52 casesof primary breast cancer,and 5 cases ofnormal mammary tissue was a-ssessed with ABC immunoperoxidasehistochemical assay and Y hepten specificnomoclonal antibody.0|4|0Updated：2026-03-12
- Abstract：<正> The beneficial dffects of human fetal liver cells on the D-galactosamine-inducedfulminant hepatic failure were observed in rats and the mechanisms of the effects investi-gated.The survival rate of the rats intraperitoneally injected with liver cell suspensionand cytosol was 47.37% and 42.11% respectively which was significantly higher than5.26% of the controls（P<0.05）.There was no statistical significance between the differ-ence of the survival rates due to two preparations.The administration of cytosol two hours before the intoduction of D-galactosamine re-sulted in a significant lowering of the plasma level of endotoxin and hepaticmalondialdehyde in rats and a marked increase of 3H-thymindinc incorporation intohepatic DNA(DPM/OD260)as compared with the parameters of the controls.These re-sults suggest that there might be some biological active substance in human fetal liver cellswhich is responsible for thc effects to increase the survival rate.0|8|0Updated：2026-03-12
- Abstract：<正> The endothelial cells of the corneas of rabbits preserved by desiccation for vari-ous duration showed no hexagonal form of normal cells but broad bean-like nuclci afterdouble staining with alizarin red and trypan blue.Scanning electron microscopic examina-tion revealed interdigitation at the intercellular junction together with intercellularvacuoles and cellular edema.Transmission electron microscopic examination showedincomplete nuclear membrane,karyopyknosis,vacuoles and remnant organellae in thecytoplasm.Partial penetrating keratoplasties were done in 37 rabbits（37 eyes）with pre-served corneas.The grafts remained transparent for a minimum of 4 days to a maximumof over 1 year,and 7 grafts remained transparent for more than 30 days.Staining ofthe transparent grafts revealed normal hexagonal endothelial cells in mosaic arrange-ment.We assumed that after transplantation of the preserved cornea the endothelial cellsregained their activities owing to the nutrient effect of the aqueous humor.0|4|0Updated：2026-03-12
- Abstract：<正> The expressions of ets-2 ,IGF-Ⅱ,C-myc and N-ras in 12 pairs ofhuman primary hepatocellular carcinoma（PHC）and tumor-adjacent tissues are presentedin this paper.The results showed that there was at least one of the four oncogenesstudied over-expressed in the 12 pairs of samples.Ets-2 was the most commonly ex-pressed oncogene seen in all the PHC and tumor-adjacent tissues,with 3.5 and 2.4 Kb asthe major two bands,which are different from the evenly expressed 4.5 ,3.5 and 2.4 Kbbands in the normal control livers.In 6 tumor-adjacent tissues,the expression ofets-2 was higher than that in PHC.IGF-Ⅱ was expressed as 5.0 and 2.0 Kb fetaltranscripts in PHC and tumor-adjacent tissues,while in the normal control livers thetranscript was 5.6 Kb only.In one tumor-adjacent tissue there were IGF-Ⅱ fetal tran-scripts ,but in the corresponding PHC no IGF-Ⅱ transcripts were detected .N-raswas expressed as 4.0 kb band in 8 out of 12 PHC and in 6 out of 12 tumor-adjacent tis-sues.In two cases the expression of N-ras was higher in tumor-adjacent tissues than inPBC.5.6 and 2.6 Kb N-ras transcripts were also detected in one pair of PHC and tumor-adjacent tissues and in two tumor-adjacent tisues only,together with the 4.0 Kbtranscript.C-myc was expressed as 4.0 Kb band in 9 out of 12 PHC and in 6 out of12 tumor-adjacent tissues.One tumor-adjacent tissue had higher C-myc expression thanPHC In two PHC ,a 2.2 Kb C-myc transcript was also detected.The roles and rela-tionships of these oncogenes in the carcinogenesis of human PHC are discussed.0|15|0Updated：2026-03-12
- Abstract：<正> Endoscopic biopsies from the distal ileal mucosa in 366 subjects with suspectedlower gastrointestinal disease and 81 normal volunteers were examined comparatively withlight microscope,scanning electron microscope（SEM）and ilcoscopy.Mucosal atrophyof distal ileum were found in 21 cases.Endoscopically the atrophied ileal mucosa pre-sented a pale red colour and the twiggy vessels were distinct.The lumen of the distalileum was usually dilated.Histopathological and SEM study of the above 21 patientsand 81 normal volunteers was carried out.Heal biopsy samples were marked with Indianink on the mucosal surface,and serially sectioned after their orientation was defined.The range of villou height was 0-320 μm,averaging 185±164 μm in the ilcal mucosalatrophy group（IMAG）,whereas it was 370-500 μn,averaging 416±22 μm in thenormal volunteers.The difference between the normal group and the IMAG was signifi-cant ,P<0.001 ,The atrophied ilcal mucosa could bc divided into four grades accordingto its villous height,our definition is as follows :Grade 0-from lower limit of normalvalue to 300 μm is a height which suggests that mucosal atrophy might bc present:Grade 1-300-200 μm is difincd as slight mucosal atrophy;Grade 2 200-100μm,moderate mucosal atrophy;Grade 3 from 100 μm to disappcarance of villi,severemucosal atrophy.Villous atrophy was found not in proportion to the cxtent of mucosalinflammation.Atrophied villi under microscope showed a shortened ,battlement-like ap-pearance.Sometimes the villi had disappeared.Under SEM,the villi appeared shor-tened,papilla-like or gyrus-like.0|5|0Updated：2026-03-12
- Abstract：<正> The auditory brainstern responses（ABR）and middle latency responses（MLR）were recorded in 24 normal mice with a 7S11A processor,and the normalparameters of ABR and MLR obtained.The results showed that the ABR of mice werecomposed of 6 waves,waves Ⅰ to Ⅵ.The mean threshold was 35.12±8.03 dB ,whichwas significantly different from the 22.63 dB of ABR found in guinea pigs.Thelatency of ABR waves Ⅰ to Ⅵizn the mice was found to be 1.30±8.03 ms ;2.02±0.24ms ;2.90±0.27 ms ;3.80±0.24 ms ;4.87±0.42 ms and 5.83±0.40 ms respectively.Nosex or strain differences were found.The MLR waveform of the mice were similar tothose of human and the latency was found to be P0 3.94±1.76 ms;P8.38±1.57ms;Na 14.98±2.54 ms;Pa 24.56±3.15 ms rcspectively.It is suggested that mice can beused for hearing research.Since the Na and Pa waves of MLR were unstable under anes-thesia,testing conditions for determining MLR in mice need further study.0|7|0Updated：2026-03-12
- Abstract：<正> The effect of 1,25-dihydroxyvitamin D3 [1,25（OH）2D3] and13-cis-retinoic acid（RA）on the proliferation of a novel human megakaryoblasticleukemia cell line（HIMeg）was investigated.At the concentration of 109 106mol/L,1,25（OH）2D3 and RA showed significant inhibition of the proliferation of themegakaryoblastic leukemic cells,which was demonstrated by the count of survival cells,incorporation of3H-TdR and3H-UR,and cloning efficiency in dose-dependent and time-dependent manners.The results can further explain the mechanism of differentiation-inducing agents and the effect of 1 ,25（OH）2D3 on myelofibrosis.It is possible for1,25（OH）2D3 and RA to be used to treat malignant megakaryocytic diseases.0|5|0Updated：2026-03-12
- Abstract：<正> By using silver colloid staining technique,nucleolar organizer region-associated proteins（AgNORs）were studied quantatively in paraffin sections of 12 casesof polypoid adenomas,10 cases of villous adenomas,22 cases of colonadenocarcinomas,and 10 cases of normal colonic mucosa as control.The resultsshowed that the mean number of AgNORs per nucleus in the villous adcnoma was similarto that of adenocaranoma,which significantly exceeded those of the normal mucosa andthe polypoid adenoma.The granules of AgNORs in adcnocarcinoma were much largerand more irregular in sizc and shape.It is suggested that benign villous adenoma is akind of lesion between polypoid adenoma and adenocarcinoma,and AgNOR techniquemay be very helpful in differential diagnosis of colon tumors.0|4|0Updated：2026-03-12
- Abstract：<正> The contents of intralymphocytic cyclic nucleotide（cAMP and cGMP）and cal-cium ions(Ca++)were determined in 20 patients with refractory congestive heart failure be-fore and after the treatment of Chinese-made amrinone,and their cardiac index was alsomcasured with the thermodilution technique.It was found that the cAMP andCa++contents were markedly elevated while the cardiac index increased under amrinonctreatment,and that both the cAMP and Cacontents were in positive correlation withthe cardiac index before and after amrinone administration.It is suggested that amrinone is likcly to exert its positive inotropic effect on themyocardium through augmenting the cAMP and Ca++contents in myocardial cells,andthat the determination of intralymphocytic cyclic nuclcotidc and Ca++might bc of signifi-canoe to assess the impairment of cardiac function and the cfficacy of a thcrapcuticagent.0|6|0Updated：2026-03-12
- Abstract：<正> In our experiment it was found that,in guinea pig papillary muscles,8205 de-creased the automaticity and prolonged the functional refractory period（FRP）as well asdecreased the contractile amplitude dose-dependently,but exerted no effect on the excitabili-ty.The dose-response curves of isoproterenol shifted to the right in parallel manner,inaccordance with competitive antagonistic,but the effect of 8205 was much less than thatof propranolol.Dose-response curves of CaCl2 shifted to the right non-parallelly.The re-sults indicated that the mechanism of anti-arrhythmia of 8205 might be related to theCa2+-antagonism.0|5|0Updated：2026-03-12
- Abstract：<正> The macro-micro-anatomy of the lingual artery of 25 adult cadavers wasstudied.The origin of the artery is rather concentrated and the greater cornu of thehyoid bone can be used as the indicator.The entrance of the artery into the hyoglossusmuscle is almost constantly along the posterior border of the muscle,where the artery issuperficially located and easily to be exposed,and has a constant relationship with thevein and hypoglossal nerve.Thus the lingual artery can be used as the artery of a recipientarea in case of tongue reconstruction.The deep lingual artery has two types ofbranches;the short ones mainly supply the muscles of tongue while the long ones mainlysupply the mucosa by forming a submucosal network.In the muscles of tongue,minutearterioles run tortuously along the muscular fibers with abundant anastomoses betweeneach other,but no anastomosis is found to cross over the rnidline of the tongue.Be-neath the mucosa,there is an arterial network spreading all over the whole tongue notlimited to one side.The relationship of the arterial architecture to the structure and thefunctions of the tongue and its clinical significance were discussed.0|6|0Updated：2026-03-12
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