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Volume ， Issue 1 ， 1986
- Abstract：<正> Thirty-five strains of HFRS virus isolated from the patients andseveral host animals in various areas in China were analyzed by IFATwith 10 McAbs specific for HFRS virus.It has been proved that thereare antigenic differences among the strains.The HFRS virus strainsrevealed nine different reactions for the McAb,showing that there are atleast nine different antigenic determinants,including group-,type-andstrain-specific.The analytical result shows that antigenic differencesamong the HFRS virus strains are mainly related to difference in the hostanimals.0|6|0Updated：2026-03-12
- Abstract：<正> The plasmids pBR322 and RSF1010,extracted from E.coli HB802 and E.coliC600 respectively,were treated with restrictive endonuclease EcoRI andligated with T4 DNA Iigase.C600 strains were then transformed with thehybrid plasmid（pSMMl）,and thus253transformants were obtained.Thefigures of gel electrophoresis and electromicrograph proved that pSMMlwas a pBR322:RSF1010 composite hybrid.In E.coli C600 pSMMl obtainedresistance against ampieilline（Ap）,tetracycline（Tc）and streptomycin（Sm）.The orientation of pBR322 and RSF1010 in hybrid pSMMl and the failureof introduction of this hybrid into P.putida AC10 were discussed.0|3|0Updated：2026-03-12
- Abstract：<正> From a population with high hapatitis B virus（HBV）infection,289liver biopsies were performed,including39cases of chronic asymptomatichepatitis（ASH）,218 chronic asymptomatic carrier（AsC）,10 transientcarriers and22cases after ending of carrier status.Among AsC,therewere 7.3% of chronic active hepatiti（CAH）,22.0% of chronic persistenthepatitis（CPH）,10.6% of chronic lobular hepatitis（CLH）,48.2% of mi-nimal changes,and 11.9% of normal liver histology.The pathologicalchanges of AsH were more severe,that of transient carriers milder andsome after carrier status cases had still remained chronic hepatitis.Among257cases with chronic HBV infection there were 26（10.1%）asymptomaticCAH,and 61（23.7%）asymptomatic CPH,their importance in the compo-sition of HBV infections was emphasied.48.2% of AsC were the cases ofminimal changes,which might be a quite stable status of hypo-reactivity toprolonged HBV infection.From the above results,the clinico-pathologicalfeatures of HBV infection in high pravalence area might be:numerousasymptomatic infections and hypo-reactive type of infection status,but highfrequency of liver lesions,although most of them were mild.0|0|0Updated：2026-03-12
- Abstract：<正> Experimental crush syndrome was established in rabbits and the renaltissues were studied with electron microscope.It was found that apartfrom the damages to the renal tubules,the ultrastructural changes of theglomeruli were also prominent,and were characterized by the following:（1）Hypertrophy and hyperplasia of the glomerular cells resulting in nar-rowing and/or obliteration of the capillary loops.（2）Retrogressive changesof the glomerular cells in varying degrees such as mitochondrial swelling,dilatation of endoplasmic reticulum,vacuole formation,etc.On the basisof the morphological findings of the renal tissues in association with theclinical manifestations of acute renal failure,it is proposed that in additionto the damages of the renal tubules,a reduction of the glomerular filtrationrate,which is the result of the altered hemodynamics in the renal vesselsalso plays an important role in the pathogenesis of acute renal failure.0|7|1Updated：2026-03-12
- Abstract：<正> The pressure changes produced by firing bullets of 7.62mm and 5.56mmand steel sphere of 1.03g through water and 20% gelatin blocks werestudied.The pressure was measured by a transducer of Model B-J 1000.It was demonstrated that there were three peaks produced when thetwo kinds of bullets were fired through a water tank.The interval betweentwo successive peaks was longer in the waves produced by the 7.62mmbullet than in those produced by the 5.56mm bullet.The peak value ofthe 5.56mm bullet was the largest,that of the 7.62mm bullet the second,and that of 1.03g steel sphere the lowest.The fore-mentioned differences among the pressures produced by differentprojectiles were dependent on their respective ballistic characteristics.Thepressure value detected and the patterns of the pressure changes were closelyrelated to the temporary cavity effect and the characteristics of tissue da-mage.0|1|0Updated：2026-03-12
- Abstract：<正> Thirty-six male Sprague-Dawley rats were used and divided into 3 groups（N=12）:simple hemorrhagic shock group,salinetreated group,and naloxone-treated group.A new method by synchronous video tape recording with 2cameras simple was established to observe the relationship between the changeof blood pressure and that of microcirculation of cremaster muscle.It wasshown that the plugging of WBC in capillaries might be the reason for noreflow in microvessels after transfusion and infusion during irreversibleshock state.Administration of naloxone followed by reinfusion of the shedblood increased blood pressure and pulse pressure.With the increase of pulsepressure a pulsed blood flow rushed the stationary of blood cells in capil-laries,which eventually pushed them away and led to reperfusion in capillaries.This made blood pressure and velocity of blood flow increase withsteadiness.The 24-hour survival rate was significantly increased in naloxone-treated group（10/12）,as compared with that in saline-treated group（1/12）.The mechanism of naloxone treatment was discussed.It was suggested thatthe effects of cardiac and microcirculatory event may influence each other,which plays an important role in the pathogenesis of irreversible hemorrhagicshock.0|3|0Updated：2026-03-12
- Abstract：<正> This experiment was designed to evaluate the osteogenetic effects ofdifferent forms of allogenic decalcified bone matrix.39 rabbits were em-ployed and a bony defect of 1cm in length was made on the shaft of theulnas of the animals.They were divided into 4 groups.In the first group,the bony defects were filled with allogenic decalcified bone powder,in thesecond group,with decalcified bone blocks,in the third group,with unde-calcified bone blocks,and in the fourth group,nothing was filled into thebony defects.Roentgenological and histological studies were made regularly.It was found that after 8-10weeks,70-80% of the bony defects filledwith DBM showed firm union between the host bone and the graftedmaterial and no difference of the osteogenecity could be found between thetwo kinds of DBM,incomplete union occurred in the third group,andnonunion was seen in the fourth group.It is suggested that allogenic decalcified bone powder be used as a graftma-terial to fill up bony defects or cavities because it is easily preparedand used,has good plasticity,and can be stored in room temperature.0|2|0Updated：2026-03-12
- Abstract：<正> The immunofluorescent cytochemical method was used to test VCA-IgAantibody of serum EB virus in 31 cases of nasopharyngeal carcinoma andin 13 patients with non-nasopharyngeal carcinoma.The positive rate ofVCA-IgA antibody was 89.28% in nasopharyngeal carcinoma patients.Sixcases of other malignant tumors of the head and neck were negative.Fivein 7 cases of chronic inflammation of nasopharyngeal mucosa were alsonegative.The control experiments manifested no false positivity or nega-tivity.The results suggest that VCA-IgA antibody of EB virus has definitespecificity in nasopharyngeal carcinoma patients.EB virus probably hasetiologic significance.This paper demonstrates the intimate relationship between EB virus andpoorly differentiated squamous carcinoma,whereas well differentiated squ-amous carcinoma and adenocarcinoma may probably bear no relation to EBvirus.Clinical observations confirm that VCA-IgA antibody test is of somevalue in early and differential diagnosis of nasopharyngeal carcinoma.0|2|0Updated：2026-03-12
- Abstract：<正> This paper is to report the experience of establishing a natural matingcolony of A.dirus with-two different sized cages in laboratory conditions.In the large cage of 50×50×100cm in size,the mosquito colonyhas been propagated to the 42nd generation,and the natural mating ratewas stablized around 80% with a highest rate of 90.63%.In the small cageof 31×20×22cm in size,the mosquito colony,which was transferredfrom the 15th generation of the large cage colony,has been propagated tothe 28th generation,and the natural mating rate of the 14th generationreached 68.96% and the highest mating rate reached 80.36%.We havesatisfactorily accomplished the task to continue the natural mating colonyof A.dirus in the small cages as well as in the large cage,0|0|1Updated：2026-03-12
- Abstract：<正> This paper reported 15 patients with cardiac failure undergoing emer-gency heart valve replacement.According to the different clinical andpahological conditions,these cases were divided into three groups:（1）acuterheumatic pancarditis;（2）acute attack of chronic heart failure;（3）acutebacterial endocarditis.There were 2 aortic valve replacements and 13 mitralvalve replacements,6 of the patients died early postoperatively and 9 ofthem remained long-term survivors,7 patients survived more than 1 yearand resumed their work.The indications for emergency heart valvereplacement,characteristic features of operative technique,and postoperativemanagements were discussed.0|5|0Updated：2026-03-12
- Abstract：<正> 480 patients with 1019 Leukoplakic lesions were studied and followedup for 5 years,none of them had malignant changes.Among the 401 smo-kers 385（96.01%）had smoking habit for 11 years.Method of odds ratiowas used for analysis,and it was found that the lesions in both smokersand non-smokers could“regress”but 3 times more in the latter than inthe former.“Aggravated cases could be seen in both smoking and non-smok-ing groups but their difference was not significant.“New lesion”,werefound in both groups too,but more than 3 times in the smoking group.TheLeukoplakic lesions were changeable rather than static,and were most ob-vious in those on the buccal sites.0|10|0Updated：2026-03-12
- Abstract：<正> In our hospital,from Jan.1960 to May 1985,28 cases had undergonereoperation.In 17 of these patients,hepatectomy was performed twice orthrice,in 4,extirpation of extrahepatic metastases after curative lobectomyand removal of a giant tumor by a two-stage operation in 7 who had un-dergone hepatic artery ligation or intraoperative embolization as a pretreat-ment to reduce the tumor’s size.Follow-up results:In the entire group,the 1-,3-,S-year survival rates after the first operation were 96.4%,77.8%,and 62.2% respectively,while the 1-3 year survival rate after the secondoperation was 60.8%,55.0% and 44.0% respectively.The preliminary resultsof reoperation are encouraging.The data have also analysed with referenceof indications for surgical reintervention,types of operation,the timingof the second laparotomy for resection of a relatively large tumor,pro-phylactivel measures against tumor recurrence and metastases and evaluationof reoperation.0|7|0Updated：2026-03-12
- Abstract：<正> The mutagenicities of 22 kinds of foods,including soy sauce,fish sauce,shrimp paste,sausages,sundried fishes,rice cracker,deep fried pork skin,salted vegetable and spices after nitrite treatment,were detected by meansof Ames test with preincubation.Mutagenicity assay was employed on Sal-monella typhimurium TA100,and meanwhile,the validity of each experi-ment was checked by using the known mutagen,AF-2,as the positivecontrol.16 kinds of foods showed marked direct-acting mutagenicity towardSalmonella typhimurium TA100 after nitrite treatment.Shrimp paste prod-uced in Bankok was the strongest one among these samples.Its specificmutagenicity was 37000 revertants/g.The amount of precursor,tyramine,in shrimp paste was estimated fromthe area of tyramine peak on HPLC by using the authentic tyramine as thestandard.Results showed that one gram shrimp paste contained 439μgtyramine.The mutagenicities of foods suggested that nitrosatable precursors,suchas amine or amide,were present in foods,and they could be converted intoendogenous carcinogen,nitrosamine,in vivo.Therefore,detection of muta-genicities of foods has significance in preventing cancer.0|16|0Updated：2026-03-12
- Abstract：<正> Six basic types of fibroblasts（low-differentiated fibroblast,young fibrobla-st,collagenoblast,myofibroblast,fibroclast and fibrocyte）were studied ultras-tructurally.In each of its three phases（prophase,metaphase and telophase）,the collagenoblast showed different functional conditions.The fibroclastscontain two subtypes,the phagocysis and the lysosome subtypes,The fibro-cytes consist two subtypes,the resting and aging subtypes.The observationsdemonstrate that the fibroblasts were derived from undifferentiated cellsaround capillaries and the low-differentiated fibroblasts are the youngestcell type of all fibroblasts.The collagenoblasts and fibroclasts are the maincells responsible for collagen biosynthesis and desrdation respectively.In the present paper a new concept,the“Fibroblast System”,has beenproposed,which includes the six basic types of fibroblasts and the stru-cturel as well as functional relationships among them.0|3|0Updated：2026-03-12
- Abstract：<正> To study the relationship between OLS and adrenergic neurotransmis-sion is the purpose of this work.The inhibitory effect of phentolamine(5×10-8M)on OLS was observed.The results showed that on the basiccontraction of myenteric plexus longitudinal muscle（MPLM）,phentolaminehad no direct effects;phentolamine could not antagonize the light dose(2×10-7M)of NE-inhibitory on MPLM basic contraction;light dose phento-1amine could antagonize the inhibitory effect of OLS induced by high fre-quence（10Hz）stimulation to the MPLM basic contraction;phentolaminecould potentiate the effect of naloxone in antagonizing the OLS. For re-searching the interaction of adrenergic and enkephalinergic neurotransmis-sion,the present results may be helpful,and also provide a new idea aboutresearching the reeeptokinetics of two types of receptor.0|3|0Updated：2026-03-12
- Abstract：<正> Experiments were performed on 19 vagotomized,curareparalyzed andartificially ventilated rabbits.3-5 barrel glass micropipettes were used torecord the extracellular discharges and to apply the ionized substances tested.Medullary respiratory units located in the region of Nucleus Treactus Soli-tarius were tested for their responsiveness to iontophoretically appliedGABA.GABA tended to inhibit not only inspiratory units but also expi-ratory ones.Of 60 units tested,49 were inhibited and the inhibitoryeffect of GABA had much to do with its quantity ejected.Phrenic nervedischarges were unchanged while the discharges of respiratory units weredepressed by GABA.The inhibitory effect of GABA could be blocked bypicrotoxin.Our results indicate that GABA may be one of the importantinhibitory neurotransmitters in the medullary“respiratory center”.0|1|0Updated：2026-03-12
- Abstract：<正> The problem of passing,fibers is an important but unsolved problemin horseradish peroxidase（HRP）tract tracing technique.Evidence has beenprovided in this study that（1）the passing fibers can be retrogradely la-beled though rather weakly and（2）the passing fibers cannot be antero-gradely labeled for long distances.0|8|0Updated：2026-03-12
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