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Neuronal Panx1 drives peripheral sensitization in experimental plantar inflammatory pain
RESEARCH | Updated：2025-12-13
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    • Neuronal Panx1 drives peripheral sensitization in experimental plantar inflammatory pain

    • “On December 13, 2025, a team of experts led by David C. Spray from the School of Dominick P. Purpura Department of NeuroscienceandQu Xing, Fang-Xia Guan from the School of School of Life Sciencespublished an article in the MMR, reveals neuronal Panx1 drives inflammatory pain through cell-autonomous excitability effects, contrasting with glial roles in orofacial pain.”
    • Qu Xing , Antonio Cibelli , Greta Luyuan Yang , Preeti Dohare , Qing-Hua Li , Eliana Scemes , Fang-Xia Guan , David C. Spray
    • Military Medical Research Vol. 12, Issue 2, Pages: 204-219(2025)

    • DOI： 10.1186/s40779-024-00525-8     

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