Advancements in understanding tumor-resident bacteria and their application in cancer therapy

Yi-Chen Luo; Xiu-Ting Huang; Rui Wang; Yu-Jing Lin; Jia-Xin Sun; Ke-Feng Li; De-Yun Wang; Yan Yan; Yong-Kang Qiao

doi:10.1186/s40779-025-00623-1

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Advancements in understanding tumor-resident bacteria and their application in cancer therapy

REVIEW | Updated：2026-01-27

- Advancements in understanding tumor-resident bacteria and their application in cancer therapy
- Advancements in understanding tumor-resident bacteria and their application in cancer therapy
- “下一代测序和生物信息学的最新进展促使人们对肿瘤内微生物群，特别是细胞内细菌在肿瘤进化过程中的不同作用越来越感兴趣。本综述探讨了癌症细胞的来源、侵袭机制以及细胞内细菌在肿瘤中的潜在生存策略，强调了它们在癌症发展中的关键作用。xx专家建立了xx系统，为解决xx问题提供了解决方案，为xx系统的建设奠定了基础。”
- Military Medical Research 2025年12卷第12期页码：1941-1983
- Affiliations：
  
  1.Centre for Biological Science and Technology, Key Laboratory of Cell Proliferation and Regulation Biology of Ministry of Education, Department of Biology, Faculty of Arts and Sciences, Guangdong Zhuhai-Macao Joint Biotech Laboratory, Beijing Normal University, Zhuhai 519087, Guangdong, China
  2.Department of Pathology, the Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai 519000, Guangdong, China
  3.Guangdong-Hong Kong-Macao University Joint Laboratory of Interventional Medicine, the Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai 519000, Guangdong, China
  4.School of Medicine, Sun Yat-Sen University, Shenzhen 518055, Guangdong, China
  5.Faculty of Applied Sciences, Macao Polytechnic University, Macau SAR 999078, China
  6.Department of Otolaryngology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Singapore 119228, Singapore
- Author bio：
  
  * Yong-Kang Qiao ykqiao@bnu.edu.cn
- Funds：
  
  the National Natural Science Foundation of China(82002612;82170029);the Fundamental Research Funds for the Central Universities, the College Students’ Innovation and Entrepreneurship Training Program(202311512);the Macao Polytechnic University(RP/FCA-14/2023);the Science and Technology Development Fund of Macao (FDCT)(0033/2023/RIB2)
- DOI：10.1186/s40779-025-00623-1
  中图分类号：
- 收稿：2024-09-05，
  
  录用：2025-07-01，
  
  网络首发：2025-07-25，
  
  纸质出版：2025-12
- Accepted：
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Yi-Chen Luo, Xiu-Ting Huang, Rui Wang, 等. Advancements in understanding tumor-resident bacteria and their application in cancer therapy[J]. Military Medical Research, 2025,12(12):1941-1983.

Yi-Chen Luo, Xiu-Ting Huang, Rui Wang, et al. Advancements in understanding tumor-resident bacteria and their application in cancer therapy[J]. Military Medical Research, 2025, 12(12): 1941-1983.
Yi-Chen Luo, Xiu-Ting Huang, Rui Wang, 等. Advancements in understanding tumor-resident bacteria and their application in cancer therapy[J]. Military Medical Research, 2025,12(12):1941-1983. DOI： 10.1186/s40779-025-00623-1.

Yi-Chen Luo, Xiu-Ting Huang, Rui Wang, et al. Advancements in understanding tumor-resident bacteria and their application in cancer therapy[J]. Military Medical Research, 2025, 12(12): 1941-1983. DOI： 10.1186/s40779-025-00623-1.

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Advancements in understanding tumor-resident bacteria and their application in cancer therapy

Advancements in understanding tumor-resident bacteria and their application in cancer therapy

DOI：10.1186/s40779-025-00623-1