Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice

Yun-Meng Bai; Fan Yang; Piao Luo; Lu-Lin Xie; Jun-Hui Chen; Yu-Dong Guan; Hong-Chao Zhou; Teng-Fei Xu; Hui-Wen Hao; Bing Chen; Jia-Hui Zhao; Cai-Ling Liang; Ling-Yun Dai; Qing-Shan Geng; Ji-Gang Wang

doi:10.1186/s40779-023-00441-3

您当前的位置：

首页 >

文章列表页 >

Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice

RESEARCH | 更新时间：2024-01-23

- Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice
- Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice
- “On January 23, 2024, a team of experts led by Yun-Meng Bai, Ling-Yun Dai, Qing-Shan Geng, Ji-Gang Wang from the School of Department of Nephrologypublished an article in the MMR, introduces its research progress in the field of triclosan-induced liver fibrosis. The team established a single-cell atlas of TCS-exposed mouse livers, revealing key cellular and molecular mechanisms driving hepatotoxicity, which provides solutions to solve environmental pollutant-related liver disease problems.”
- Yun-Meng Bai ，Fan Yang ，Piao Luo ，Lu-Lin Xie ，Jun-Hui Chen ，Yu-Dong Guan ，Hong-Chao Zhou ，Teng-Fei Xu ，Hui-Wen Hao ，Bing Chen ，Jia-Hui Zhao ，Cai-Ling Liang ，Ling-Yun Dai ，Qing-Shan Geng ，Ji-Gang Wang
- MMR 2023年10卷第5期页码：599-619
- 作者机构：
  1.Department of Nephrology, Shenzhen Key Laboratory of Kidney Diseases, and Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People’s Hospital, the First Affiliated Hospital, Southern University of Science and Technology, Shenzhen 518020, China
  2.Department of Urology, Shenzhen People’s Hospital, the First Affiliated Hospital, Southern University Science and Technology, the Second Clinical Medical College, Jinan University, Shenzhen 518020, China
  3.Integrated Chinese and Western Medicine Postdoctoral Research Station, Jinan University, Guangzhou 510632, China
  4.Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China
  5.Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China
  6.Center for Reproductive Medicine, Dongguan Maternal and Child Health Care Hospital, Southern Medical University, Dongguan 523125, Guangdong, China
- 作者简介：
  * dai.lingyun@szhospital.com;
  gengqingshan@gdph.org.cn;
  jgwang@icmm.ac.cn
- 基金信息：
  the National Key Research and Development Program of China(2020YFA0908000;2022YFC2303600);the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(ZYYCXTD-C-202002);the National Natural Science Foundation of China(82141001;82274182;82173914;82074098;81903588 and 82003814);the Science and Technology Foundation of Shenzhen(JCYJ20210324115800001);the Science and Technology Foundation of Shenzhen (Shenzhen Clinical Medical Research Center for Geriatric Diseases);the Fundamental Research Funds for the Central Public Welfare Research Institutes(ZXKT18003);the Fundamental Research Funds for the Central public welfare research institutes(ZZ14-YQ-050);the National Key R&D Program of China Key projects for international cooperation on science, technology and innovation(2020YFE0205100);the Shenzhen Governmental Sustainable Development Fund(KCXFZ20201221173612034);the Shenzhen key Laboratory of Kidney Diseases(ZDSYS201504301616234);the Shenzhen Fund for Guangdong Provincial High-level Clinical Key Specialties(SZGSP001);a Grant from the Sanming Project of Medicine in Shenzhen(SZSM201612034)
- DOI： 10.1186/s40779-023-00441-3
  中图分类号：
- 稿件说明：
移动端阅览
DOI：
DOI：

AI导读
HTML全文
图( 7 ) 表( 0 )
参考文献
出版信息
数据统计

72

浏览量

48

下载量

0

CSCD

文章被引用时，请邮件提醒。

提交

工具集

BibTeX下载
Endnote下载
RefMan 下载
NoteExpress下载
NoteFirst下载

关联资源

Maladaptive reorganization of mediodorsal thalamus as a central mechanism in neuropathic pain-related sleep disorders

Endothelial barrier and sepsis: mechanisms and potential therapeutic strategies

Frostbite: diagnosis, treatment, prognosis, and future directions

Engineered exosomes for diabetic foot ulcers: lessons learned, challenges remain

Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice

Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice

DOI： 10.1186/s40779-023-00441-3

AI导读

HTML全文

图( 7 ) 表( 0 )

参考文献

出版信息

数据统计

摘要

Abstract

关键词

Keywords

references