Activated Drp1 regulates p62-mediated autophagic flux and aggravates inflammation in cerebral ischemia-reperfusion via the ROS-RIP1/RIP3-exosome axis

Xue Zeng; Yun-Dong Zhang; Rui-Yan Ma; Yuan-Jing Chen; Xin-Ming Xiang; Dong-Yao Hou; Xue-Han Li; He Huang; Tao Li; Chen-Yang Duan

doi:10.1186/s40779-022-00383-2

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Activated Drp1 regulates p62-mediated autophagic flux and aggravates inflammation in cerebral ischemia-reperfusion via the ROS-RIP1/RIP3-exosome axis

RESEARCH | 更新时间：2023-03-20

- Activated Drp1 regulates p62-mediated autophagic flux and aggravates inflammation in cerebral ischemia-reperfusion via the ROS-RIP1/RIP3-exosome axis
- Activated Drp1 regulates p62-mediated autophagic flux and aggravates inflammation in cerebral ischemia-reperfusion via the ROS-RIP1/RIP3-exosome axis
- Xue Zeng ，Yun-Dong Zhang ，Rui-Yan Ma ，Yuan-Jing Chen ，Xin-Ming Xiang ，Dong-Yao Hou ，Xue-Han Li ，He Huang ，Tao Li ，Chen-Yang Duan
- 解放军医学杂志（英文版） 2022年9卷第6期页码：668-685
- 作者机构：
  1.Department of Anaesthesiology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China
  2.Department of Neurology, the Third Affiliated Hospital of Chongqing Medical University, Chongqing 401120, China
  3.Department of Cardiovascular Surgery, Xinqiao Hospital, Army Medical University, Chongqing 400037, China
  4.State Key Laboratory of Trauma, Burns and Combined Injury, Department of Shock and Transfusion, Daping Hospital, Army Medical University, Chongqing 400042, China
- 作者简介：
  * 13708385559@163.com;
  lt200132@126.com;
  duanchenyang1991@cqmu.edu.cn
- 基金信息：
  the National Natural Science Foundation of China(81700429);the China Postdoctoral Science Foundation(2021MD703924);the Chongqing Postdoctoral Innovative Talents Support Program(CQBX2021018);the Kuanren Talents Program of the second affiliated hospital of Chongqing Medical University
- DOI： 10.1186/s40779-022-00383-2
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