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Biomarcadores de autoanticorpos de exossomos para detecção do câncer de pulmão

  • role： Contribute equally, First author同等贡献者, 第一作者
  • Affiliation：

    Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore

Win Lwin Thuya1,  
  • role： Contribute equally同等贡献者
  • Affiliation：

    Sengenics Corporation, Jalan Kerinchi, Bangsar South, 59200 Kuala Lumpur, Malaysia

    University of Cape Town, Cape Town 7700, South Africa

Janique Michelle Peyper23,  
  • Affiliation：

    Sengenics Corporation, Jalan Kerinchi, Bangsar South, 59200 Kuala Lumpur, Malaysia

Tan Ti Myen2,  
  • Affiliation：

    Sengenics Corporation, Jalan Kerinchi, Bangsar South, 59200 Kuala Lumpur, Malaysia

Nur Diana Anuar2,  
  • Affiliation：

    Sengenics Corporation, Jalan Kerinchi, Bangsar South, 59200 Kuala Lumpur, Malaysia

Arif Anwar2,  
  • Affiliation：

    Sengenics Corporation, Jalan Kerinchi, Bangsar South, 59200 Kuala Lumpur, Malaysia

Ranga Gudimella2,  
  • Affiliation：

    Sengenics Corporation, Jalan Kerinchi, Bangsar South, 59200 Kuala Lumpur, Malaysia

Nurul Huda Rutt2,  
  • Affiliation：

    Sengenics Corporation, Jalan Kerinchi, Bangsar South, 59200 Kuala Lumpur, Malaysia

Nurul Shielawati Mohamed Rosli2,  
  • Affiliation：

    Sengenics Corporation, Jalan Kerinchi, Bangsar South, 59200 Kuala Lumpur, Malaysia

Noorul Hidayah Badri2,  
  • Affiliation：

    Sengenics Corporation, Jalan Kerinchi, Bangsar South, 59200 Kuala Lumpur, Malaysia

Teh Norleila Abdul Rahman2,  
  • Affiliation：

    Sengenics Corporation, Jalan Kerinchi, Bangsar South, 59200 Kuala Lumpur, Malaysia

Raja Nurashirin2,  
  • Affiliation：

    Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore

    NUS Centre for Cancer Research (N2CR), Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore

Gautam Sethi45,  
  • Affiliation：

    Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, 15 1E Kent Ridge Road, Singapore 119228, Singapore

John Kit Chung Tam6,  
  • Affiliation：

    Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore

    NUS Centre for Cancer Research (N2CR), Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore

    Department of Haematology-Oncology, National University Cancer Institute, National 17 University Health System, Singapore 119228, Singapore

Andrea Li-Ann Wong157,  
  • Affiliation：

    Department of Haematology-Oncology, National University Cancer Institute, National 17 University Health System, Singapore 119228, Singapore

Ross Soo7,  
  • Affiliation：

    Sengenics Corporation, Jalan Kerinchi, Bangsar South, 59200 Kuala Lumpur, Malaysia

    University of Cape Town, Cape Town 7700, South Africa

Jonathan M. Blackburn23,  
  • role： Corresponding author通信作者
  • Affiliation：

    Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore

    Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore

    NUS Centre for Cancer Research (N2CR), Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore

  • Email：csiwl@nus.edu.sg
  • Introduction：* csiwl@nus.edu.sg
Ling-Zhi Wang145*,  
  • role： Corresponding author通信作者
  • Affiliation：

    Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore

    Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore

    NUS Centre for Cancer Research (N2CR), Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore

    Department of Haematology-Oncology, National University Cancer Institute, National 17 University Health System, Singapore 119228, Singapore

  • Email：phcgbc@nus.edu.sg
  • Introduction：phcgbc@nus.edu.sg
Boon Cher Goh1457*

Resumo

Palavras-chave

Non-small cell lung cancer (NSCLC);Tumour-derived exosomes;Autoantibodies;diagnosis;prognosis

References

  1. 1..
    Chen X, Mo S, Yi B. The spatiotemporal dynamics of lung cancer: 30-year trends of epidemiology across 204 countries and territories. BMC Public Health. 2022;22(1):987.
  2. 2..
    Duma N, Santana-Davila R, Molina JR. Non-small cell lung cancer: epidemiology, screening, diagnosis, and treatment. Mayo Clin Proc. 2019;94(8):1623-40.
  3. 3..
    Yang B, Li X, Ren T, Yin Y. Autoantibodies as diagnostic biomarkers for lung cancer: a systematic review. Cell Death Discov. 2019;5:126.
  4. 4..
    Ministry of Health. MOH Clinical Practice Guidelines. 2010. Available at: .
  5. 5..
    Huang T, Deng CX. Current progresses of exosomes as cancer diagnostic and prognostic biomarkers. Int J Biol Sci. 2019;15(1):1-11.

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