診断の可能性を探る:脳疾患における磁気粒子イメージング

  • role: Contribute equally, First author同等贡献者, 第一作者
  • Affiliation:

    School of Engineering Medicine, Beihang University, Beijing 100191, China

    School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China

Li-Shuang Guo12,  
  • role: Contribute equally同等贡献者
  • Affiliation:

    School of Engineering Medicine, Beihang University, Beijing 100191, China

    Key Laboratory of Big Data-Based Precision Medicine (Beihang University), Ministry of Industry and Information Technology of China, Beijing 100191, China

Yu An13,  
  • role: Contribute equally同等贡献者
  • Affiliation:

    School of Engineering Medicine, Beihang University, Beijing 100191, China

    Key Laboratory of Big Data-Based Precision Medicine (Beihang University), Ministry of Industry and Information Technology of China, Beijing 100191, China

Ze-Yu Zhang13,  
  • Affiliation:

    School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China

Chen-Bin Ma2,  
  • Affiliation:

    School of Engineering Medicine, Beihang University, Beijing 100191, China

    School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China

Jia-Qian Li12,  
  • Affiliation:

    School of Engineering Medicine, Beihang University, Beijing 100191, China

    School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China

Zhen Dong12,  
  • role: Corresponding author通信作者
  • Affiliation:

    School of Engineering Medicine, Beihang University, Beijing 100191, China

    Key Laboratory of Big Data-Based Precision Medicine (Beihang University), Ministry of Industry and Information Technology of China, Beijing 100191, China

    CAS Key Laboratory of Molecular Imaging, Institute of Automation, Beijing 100191, China

  • Email:tian@ieee.org
  • Introduction:* Jie Tian tian@ieee.org
Jie Tian134*,  
  • role: Corresponding author通信作者
  • Affiliation:

    CAS Key Laboratory of Molecular Imaging, Institute of Automation, Beijing 100191, China

    University of Chinese Academy of Sciences, Beijing 100080, China

  • Email:zhenyu.liu@ia.ac.cn
  • Introduction:Zhen-Yu Liu zhenyu.liu@ia.ac.cn
Zhen-Yu Liu45*,  
  • role: Corresponding author通信作者
  • Affiliation:

    School of Engineering Medicine, Beihang University, Beijing 100191, China

    Key Laboratory of Big Data-Based Precision Medicine (Beihang University), Ministry of Industry and Information Technology of China, Beijing 100191, China

  • Email:jgliu@buaa.edu.cn
  • Introduction:Jian-Gang Liu jgliu@buaa.edu.cn
Jian-Gang Liu13*

サマリー

脳疾患は高い発生率、障害率、死亡率を特徴としています。その捉えどころのない性質は早期診断に大きな課題をもたらします。磁気粒子イメージング(MPI)は高感度、高時間分解能、非イオン化放射線の新しいイメージング技術です。これは超常磁性酸化鉄ナノ粒子(SPIONs)の非線形磁化応答に基づいており、生体組織内のSPIONsの空間的濃度分布の可視化を可能にします。MPIは、癌性、脳血管性、神経変性、および炎症性疾患などの脳疾患の早期診断の主流技術になることが期待されています。本総説はMPIの原理の概要を提供し、脳疾患におけるその潜在的応用を探り、これらの疾患の診断および管理の展望について議論します。

キーワード

磁気粒子イメージング;脳疾患;早期診断

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