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フランク・スターリング機構だけでは不十分：血液量増加は肺のO2摂取を著しく減少させる

  • role： First author第一作者
  • Affiliation：

    Faculty of Medicine, Hong Kong University, Hong Kong, China

Mei-Han Guo1,  
  • Affiliation：

    Department of Medicine, School of Clinical Medicine, Hong Kong University, Hong Kong, China

Candela Diaz-Canestro2,  
  • role： Corresponding author通信作者
  • Affiliation：

    Faculty of Medicine, Hong Kong University, Hong Kong, China

    Department of Medicine, School of Clinical Medicine, Hong Kong University, Hong Kong, China

    Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary T2N 4N1, Canada

  • Email：dvmb@hku.hk
  • Introduction：* dvmb@hku.hk
David Montero123*

サマリー

キーワード

Blood volume expansion;Placebo-controlled;Cross-over;Pulmonary O2 uptake;Cardiac performance;Aerobic exercise capacity;Cardiorespiratory fitness

References

  1. 1..
    Mier CM, Domenick MA, Turner NS, Wilmore JH. Changes in stroke volume and maximal aerobic capacity with increased blood volume in men women. J Appl Physiol (1985). 1996;80(4):1180–6.
  2. 2..
    Warburton DE, Gledhill N, Jamnik VK, Krip B, Card N. Induced hypervolemia, cardiac function, VO2max, and performance of elite cyclists. Med Sci Sports Exerc. 1999;31(6):800–8.
  3. 3..
    Diaz-Canestro C, Pentz B, Sehgal A, Montero D. Sex differences in cardiorespiratory fitness are explained by blood volume and oxygen carrying capacity. Cardiovasc Res. 2022;118(1):334–43.
  4. 4..
    Schierbauer J, Hoffmeister T, Treff G, Wachsmuth NB, Schmidt WFJ. Effect of exercise-induced reductions in blood volume on cardiac output and oxygen transport capacity. Front Physiol. 2021;12:679232.
  5. 5..
    Montero D, Lundby C. Regulation of red blood cell volume with exercise training. Compr Physiol. 2018;9(1):149–64.
  6. 6..
    Guo M, Diaz-Canestro C, Ng MY, Yiu KH, Montero D. Sex-specific limitation of cardiac capacity during the adult life span: return to fundamental structure and function. J Gerontol A Biol Sci Med Sci. 2024;79(3):glad255.

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