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Hydrogel GelMA injectable chargé en MSC formé in situ, combiné avec PD pour la régénération des glandes sudoripares vascularisées

  • role： Contribute equally, First author同等贡献者, 第一作者
  • Affiliation：

    Research Center for Tissue Repair and Regeneration, Medical Innovation Research Department, Chinese PLA General Hospital and PLA Medical College, Beijing 100048, China

    Institute of Basic Medical Research, Inner Mongolia Medical University, Hohhot 010110, China

Enhe Jirigala12,  
  • role： Contribute equally同等贡献者
  • Affiliation：

    Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin 300072, China

Bin Yao3,  
  • Affiliation：

    Research Center for Tissue Repair and Regeneration, Medical Innovation Research Department, Chinese PLA General Hospital and PLA Medical College, Beijing 100048, China

Zhao Li1,  
  • Affiliation：

    Research Center for Tissue Repair and Regeneration, Medical Innovation Research Department, Chinese PLA General Hospital and PLA Medical College, Beijing 100048, China

Yi-Jie Zhang1,  
  • Affiliation：

    Research Center for Tissue Repair and Regeneration, Medical Innovation Research Department, Chinese PLA General Hospital and PLA Medical College, Beijing 100048, China

    School of Medicine, Nankai University, Tianjin 300071, China

Chao Zhang14,  
  • Affiliation：

    Research Center for Tissue Repair and Regeneration, Medical Innovation Research Department, Chinese PLA General Hospital and PLA Medical College, Beijing 100048, China

Li-Ting Liang1,  
  • Affiliation：

    Research Center for Tissue Repair and Regeneration, Medical Innovation Research Department, Chinese PLA General Hospital and PLA Medical College, Beijing 100048, China

Fan-Liang Zhang1,  
  • Affiliation：

    Research Center for Tissue Repair and Regeneration, Medical Innovation Research Department, Chinese PLA General Hospital and PLA Medical College, Beijing 100048, China

Xing-Yu Yuan1,  
  • Affiliation：

    Research Center for Tissue Repair and Regeneration, Medical Innovation Research Department, Chinese PLA General Hospital and PLA Medical College, Beijing 100048, China

Xian-Lan Duan1,  
  • Affiliation：

    Research Center for Tissue Repair and Regeneration, Medical Innovation Research Department, Chinese PLA General Hospital and PLA Medical College, Beijing 100048, China

Wei Song1,  
  • Affiliation：

    Research Center for Tissue Repair and Regeneration, Medical Innovation Research Department, Chinese PLA General Hospital and PLA Medical College, Beijing 100048, China

Meng-De Zhang1,  
  • Affiliation：

    Research Center for Tissue Repair and Regeneration, Medical Innovation Research Department, Chinese PLA General Hospital and PLA Medical College, Beijing 100048, China

Yi Kong1,  
  • role： Corresponding author通信作者
  • Affiliation：

    Research Center for Tissue Repair and Regeneration, Medical Innovation Research Department, Chinese PLA General Hospital and PLA Medical College, Beijing 100048, China

  • Email：fuxiaobing@vip.sina.com
  • Introduction：* fuxiaobing@vip.sina.com;
Xiao-Bing Fu1*,  
  • role： Corresponding author通信作者
  • Affiliation：

    Research Center for Tissue Repair and Regeneration, Medical Innovation Research Department, Chinese PLA General Hospital and PLA Medical College, Beijing 100048, China

  • Email：stellarahuang@sina.com
  • Introduction：stellarahuang@sina.com
Sha Huang1*

résumé

mots-clés

Sweat gland;GelMA;In situ niche;Cell differentiation;Tissue incorporation;Vascularization

References

  1. 1..
    Yao B, Wang R, Wang Y, Zhang Y, Hu T, Song W, et al. Biochemical and structural cues of 3D-printed matrix synergistically direct MSC differentiation for functional sweat gland regeneration. Sci Adv. 2020;6(10):eaaz1094.
  2. 2..
    Yue K, Trujillo-de Santiago G, Alvarez MM, Tamayol A, Annabi N, Khademhosseini A. Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels. Biomaterials. 2015;73:254–71.
  3. 3..
    Swanson WB, Omi M, Woodbury SM, Douglas LM, Eberle M, Ma PX, et al. Scaffold pore curvature influences MSC fate through differential cellular organization and YAP/TAZ activity. Int J Mol Sci. 2022;23(9):4499.

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