Latest Issue

Volume 0 ， Issue 2 ， 1997

Studies of the antagonistic effect of BQ-123 on cerebral vasospasm induced by intracisternal injection of endothelin-1 and subarachnoid hemorrhage Cover Article Back Cover Article Enhanced Publication AI Introduction

Vol. 0, Issue 2, Pages: 83-87(1997)

Keywords：BQ-123;endothelin A-receptor antagonist;Endothelin-1;cerebral vasospasm;subarachnoid hemorrhage

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<Citation> <Bulk Citation> 32971765 false

Updated：2026-03-12
Effects of CD11/CD18 mediated PMN-EC adhesion on the endothelial cell damages in the early stage postburn in vitro Cover Article Back Cover Article Enhanced Publication AI Introduction

Vol. 0, Issue 2, Pages: 88-92(1997)

Keywords：endothelial cell;polymorphonuclear neutrophil;CDll/CD18;damage

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<Citation> <Bulk Citation> 32971712 false

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Analysis of Rb gene in primary acute lymphoid leukemia Cover Article Back Cover Article Enhanced Publication AI Introduction

Vol. 0, Issue 2, Pages: 93-95(1997)

Keywords：Rb gene;acute lymphoid leukemia;gene deletion

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<Citation> <Bulk Citation> 32972208 false

Updated：2026-03-12
In vitro proliferation and in vivo tumorigenicity of IL-2 gene and IL-3gene co-transfected leukemia cells Cover Article Back Cover Article Enhanced Publication AI Introduction

于敏, 曹雪涛, 章卫平, 杨建民, 孟沛霖
Issue 2, Pages: 96-99(1997)

Abstract：In vitro proliferation and in vivo tumorigenicity of IL-2 and/or IL-3 gene transfected FBL-3erythroleukemia cells were observed to investigate the anti-tumor effect of tumor vaccine. Methods: Leukemiacells were trans fected with IL-2 and/or IL-3 adenovlrus vector. The cytokine expressions were assayed, and the growth characteristics of the transfected FBL-3 cells were studied. Results: High levels of secreted IL-2 and IL-3remained for one week after transfection, and the trans fected leukemia cells became unchanged in growth in vitro and showed weak tumorigenicity in vlvo. The tumorigenicity of FBL-3 cells decreased more significantly when FBL-3 cells were transfected with both IL-2 gene and IL-3 gene than when FBL-3 cells were tran fected with IL-2or IL-3 gene only. The tumor growth was significantly delayed and survival time of the trans fected FBL-3 inoculat ed mice was significantly prolonged. Conclusion: The inhibition of tumor growth is most likely dependent on immune response induced by IL-2

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Concanavalin A-induced changes in lysosomal morphology of macrophages under confocal microscope Cover Article Back Cover Article Enhanced Publication AI Introduction

Vol. 0, Issue 2, Pages: 100-104(1997)

Keywords：macrophage;lysosome;concanavalin A;confocal microscope

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<Citation> <Bulk Citation> 32971505 false

Updated：2026-03-12
Effects of membrane lipids on expression and molecular properties of CD 71 in lymphocytes Cover Article Back Cover Article Enhanced Publication AI Introduction

Vol. 0, Issue 2, Pages: 105-109(1997)

Keywords：membrane lipid;lymphocyte;CD 71 protein

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<Citation> <Bulk Citation> 32971398 false

Updated：2026-03-12
Generation of bcl-2 antisense RNA promotes apoptosis of human promyelocytic leukemia cell line HL-60 Cover Article Back Cover Article Enhanced Publication AI Introduction

Vol. 0, Issue 2, Pages: 110-115(1997)

Keywords：bcl-21 antisense RNA;HL-60 cells;apoptosis

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<Citation> <Bulk Citation> 32971460 false

Updated：2026-03-12
Observation on the specific binding site of p195 protein on human erythrocytes using colloidal gold labelling Cover Article Back Cover Article Enhanced Publication AI Introduction

Vol. 0, Issue 2, Pages: 116-120(1997)

Keywords：Plasmodium falciparum;p195;colloidal gold;erythrocytes

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<Citation> <Bulk Citation> 32971654 false

Updated：2026-03-12
Effects of amniotic fluid embolism-like plasma on isolated perfused rabbit lungs Cover Article Back Cover Article Enhanced Publication AI Introduction

余艳红
Issue 2, Pages: 121-123(1997)

Abstract：Effects of amniotic fluid embolism-like plasma （AFEP） on the isolated perfused rabbit lungs （IPRL）were studied. It was found that AFEP could induce elevation of pulmonary artery pressure （PAP） and development of lung edema, which could be partially prevented by ibuprofen, a cycloxygenase inhibit0r, but amniotic fluid itself could not cause elevation of PAP and lung edema. The result suggests that AFEP-induced mediator from whole blood cells may be the important factor resulting in above-mentioned pathological changes.

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Changes of pulmonary beta-adrenergic receptors and their relationship with membranous phospholipid metabolism in endotoxin-induced lung injury in rats Cover Article Back Cover Article Enhanced Publication AI Introduction

Vol. 0, Issue 2, Pages: 124-127(1997)

Keywords：acute lung injury;endotoxin;beta-adrenergic receptor;membranous phospholipid;rat

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<Citation> <Bulk Citation> 32972149 false

Updated：2026-03-12
Implantation of xenogeneic bone combined with recombinant human bone morphogenetic protein-2 into bone defect—An scanning electron microscopic study Cover Article Back Cover Article Enhanced Publication AI Introduction

Vol. 0, Issue 2, Pages: 128-131(1997)

Keywords：recombinant human bone morphogenetic protein-2;bone transplantation;cancellous bone

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<Citation> <Bulk Citation> 32972106 false

Updated：2026-03-12
Experimental study on immunomodulation and antitumor effects of melatonin in H22 hepatoma-bearing mice Cover Article Back Cover Article Enhanced Publication AI Introduction

晏建军, 沈锋, 吴孟超
Issue 2, Pages: 132-135(1997)

Abstract：Objective: To observe immunomodulation and antitumor effect of melatonin （MLT） in tumor-bearingmice. Methods: By means of flow cytometry and MTT colorimetry, the immunological indexes of H22 hepatoma-bearing mice were investigated. Results: MLTadministration could increase the CD4t/CD8t cell ratio in the pe-ripheral blood of the tumor-bearing mice, cooperate with IL-2 to promote the proliferation of lymphocytes andeosinophils, increase NK and LAK activity of splenocytes, and enhance the production of IL-2 from splenocytes.We also found that MLT could inhibit tumor growth and prolong the survival time of the tumor-bearing mice in vi-vo. Moreover,a synergetic effect of IL-2 and MLT was observed. It seems that MLT hadno effect on H22 hep-atoma cell growth in vitro. Conclusion: It is suggested that MLT may be a potential candidate for tumor im-munotherapy as one of the biological reaction modulators （BRM）.

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Effects of highly potent atrial natriuretic peptide on circulating reninangiotensin-aldosterone system and cardiac function in dogs with ischemic heart failure Cover Article Back Cover Article Enhanced Publication AI Introduction

Vol. 0, Issue 2, Pages: 136-139(1997)

Keywords：highly potent atrial natriuretic peptide;renin-angiotensin-aldosterone system;myocardial ischemia;heart failure

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<Citation> <Bulk Citation> 32971553 false

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Effects of retinoic acid and arotinoidethylester on expression of cyclins and cyclin-dependent kinase in HL-60 cells Cover Article Back Cover Article Enhanced Publication AI Introduction

Vol. 0, Issue 2, Pages: 140-142(1997)

Keywords：retinoic acid;cyclin;P34

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<Citation> <Bulk Citation> 32971602 false

Updated：2026-03-12
Changes in activity of superoxide dismutase and content of malondialdehyde in rats with monocrotaline-induced pulmonary hypertension Cover Article Back Cover Article Enhanced Publication AI Introduction

Vol. 0, Issue 2, Pages: 143-146(1997)

Keywords：hypertension;pulmonary artery;monocrotaline;superoxide dismutase;malondialdehyde;rats

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<Citation> <Bulk Citation> 32971924 false

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The relationship between obese protein and noninsulin-dependent diabetes mellitus Cover Article Back Cover Article Enhanced Publication AI Introduction

Vol. 0, Issue 2, Pages: 147-149(1997)

Keywords：diabetes mellitus, non-insulin dependent;obese protein;radioimmunoassay

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<Citation> <Bulk Citation> 32972051 false

Updated：2026-03-12
Acute GvHD and the cutaneous ultrastructural changes in mismatched bone marrow transplantation Cover Article Back Cover Article Enhanced Publication AI Introduction

Vol. 0, Issue 2, Pages: 150-154(1997)

Keywords：human leukocyte antigen;a1logenic bone marrow transplantation;acute graft-versus-host disease;ultrastructure

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<Citation> <Bulk Citation> 32972258 false

Updated：2026-03-12
Changes of circulating TNF and its effects on Pseudomonas aeruginosa septic shock in rabbits Cover Article Back Cover Article Enhanced Publication AI Introduction

Vol. 0, Issue 2, Pages: 155-161(1997)

Keywords：stress hormone;lactic;acidl beta-glucuronidase;phagocytosis;malondialdehyde;superoxide dismutase;lipopolysaccharide;rabbits

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<Citation> <Bulk Citation> 32971875 false

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Methylene blue could transiently reverse the vasodilator effect of inhaled nitric oxide in canine hypoxic pulmonary hypertension mode Cover Article Back Cover Article Enhanced Publication AI Introduction

Vol. 0, Issue 2, Pages: 162-165(1997)

Keywords：nitric oxide;methylene blue;pulmonary hypertension;dogs

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<Citation> <Bulk Citation> 32971988 false

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Immunogenicity of recombinant attenuated Salmonella typhimurium expressing a 45-peptide hybrid antigen gene of Plasmodium falciparum Cover Article Back Cover Article Enhanced Publication AI Introduction

Vol. 0, Issue 2, Pages: 166-171(1997)

Keywords：Salmonella typhimurium;Plasmodium falciparum;hybrid antigen gene;oral live vaccine;malaria vaccine;immunogenicity

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Latest Issue

Studies of the antagonistic effect of BQ-123 on cerebral vasospasm induced by intracisternal injection of endothelin-1 and subarachnoid hemorrhage Cover Article Back Cover Article Enhanced Publication AI Introduction

Effects of CD11/CD18 mediated PMN-EC adhesion on the endothelial cell damages in the early stage postburn in vitro Cover Article Back Cover Article Enhanced Publication AI Introduction

Analysis of Rb gene in primary acute lymphoid leukemia Cover Article Back Cover Article Enhanced Publication AI Introduction

In vitro proliferation and in vivo tumorigenicity of IL-2 gene and IL-3gene co-transfected leukemia cells Cover Article Back Cover Article Enhanced Publication AI Introduction

Concanavalin A-induced changes in lysosomal morphology of macrophages under confocal microscope Cover Article Back Cover Article Enhanced Publication AI Introduction

Effects of membrane lipids on expression and molecular properties of CD 71 in lymphocytes Cover Article Back Cover Article Enhanced Publication AI Introduction

Generation of bcl-2 antisense RNA promotes apoptosis of human promyelocytic leukemia cell line HL-60 Cover Article Back Cover Article Enhanced Publication AI Introduction

Observation on the specific binding site of p195 protein on human erythrocytes using colloidal gold labelling Cover Article Back Cover Article Enhanced Publication AI Introduction

Effects of amniotic fluid embolism-like plasma on isolated perfused rabbit lungs Cover Article Back Cover Article Enhanced Publication AI Introduction

Changes of pulmonary beta-adrenergic receptors and their relationship with membranous phospholipid metabolism in endotoxin-induced lung injury in rats Cover Article Back Cover Article Enhanced Publication AI Introduction

Implantation of xenogeneic bone combined with recombinant human bone morphogenetic protein-2 into bone defect—An scanning electron microscopic study Cover Article Back Cover Article Enhanced Publication AI Introduction

Experimental study on immunomodulation and antitumor effects of melatonin in H22 hepatoma-bearing mice Cover Article Back Cover Article Enhanced Publication AI Introduction

Effects of highly potent atrial natriuretic peptide on circulating reninangiotensin-aldosterone system and cardiac function in dogs with ischemic heart failure Cover Article Back Cover Article Enhanced Publication AI Introduction

Effects of retinoic acid and arotinoidethylester on expression of cyclins and cyclin-dependent kinase in HL-60 cells Cover Article Back Cover Article Enhanced Publication AI Introduction

Changes in activity of superoxide dismutase and content of malondialdehyde in rats with monocrotaline-induced pulmonary hypertension Cover Article Back Cover Article Enhanced Publication AI Introduction

The relationship between obese protein and noninsulin-dependent diabetes mellitus Cover Article Back Cover Article Enhanced Publication AI Introduction

Acute GvHD and the cutaneous ultrastructural changes in mismatched bone marrow transplantation Cover Article Back Cover Article Enhanced Publication AI Introduction

Changes of circulating TNF and its effects on Pseudomonas aeruginosa septic shock in rabbits Cover Article Back Cover Article Enhanced Publication AI Introduction

Methylene blue could transiently reverse the vasodilator effect of inhaled nitric oxide in canine hypoxic pulmonary hypertension mode Cover Article Back Cover Article Enhanced Publication AI Introduction

Immunogenicity of recombinant attenuated Salmonella typhimurium expressing a 45-peptide hybrid antigen gene of Plasmodium falciparum Cover Article Back Cover Article Enhanced Publication AI Introduction