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PRIME: an interpretable artificial intelligence model based on liquid biopsy improves prediction of progression risk in non-small cell lung cancer
RESEARCH | Updated：2026-01-29

    • PRIME: an interpretable artificial intelligence model based on liquid biopsy improves prediction of progression risk in non-small cell lung cancer

    • “In the field of early-stage non-small cell lung cancer treatment, researchers have developed an AI-assisted model called PRIME, which integrates clinical-genomic predictors to enhance risk prediction and guide personalized therapy. The model outperforms single liquid biopsy biomarkers and clinical-therapeutic signatures, demonstrating consistent robustness across different clinical scenarios.”
    • Military Medical Research   Vol. 12, (2025)

    • DOI：10.1186/s40779-025-00679-z    

      CLC：

    • Received：26 January 2025，

      Accepted：25 November 2025，

      Online First：06 January 2026，

      Published：2025

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  • Yu Wang, Yong-Bo Xiang, Xiao-Wei Chen, et al. PRIME: an interpretable artificial intelligence model based on liquid biopsy improves prediction of progression risk in non-small cell lung cancer[J/OL]. Military Medical Research, 2025, 12. DOI： 10.1186/s40779-025-00679-z.

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