Engineered immune-driven theranostics for clinical cardiology

Jing-Ben Zheng; Xiao-Ye Li; Ji-Min Zhu; Cheng Liu; Xiao-Tian Song; Bin Wang; Yue Deng; Yu-Xiao Feng; Qi Wang; Juan Liu; Heng Dong; Xing-Jie Liang; Yuan Huang

doi:10.1186/s40779-025-00664-6

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Engineered immune-driven theranostics for clinical cardiology

REVIEW | Updated：2026-03-26

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- Engineered immune-driven theranostics for clinical cardiology
- “On March 26, 2026, a team of experts led by Jing-Ben Zheng, Heng Dong from the School of Nanjing Stomatological Hospital, Yuan Huang from the School of Department of Structural Heart Disease, Juan Liu from the School of Hepato-Pancreato-Biliary CenterandXing-Jie Liang from the School of CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafetypublished an article in the MMR, introduces its research progress in the field of nanotechnology-based cardiovascular immunotherapy. Expert team established integrated nanotheranostic platforms for immune cell regulation and real-time imaging, which provides solutions to solve precision treatment challenges in atherosclerosis, myocardial infarction and related diseases.”
- Jing-Ben Zheng , Xiao-Ye Li , Ji-Min Zhu , Cheng Liu , Xiao-Tian Song , Bin Wang , Yue Deng , Yu-Xiao Feng , Qi Wang , Juan Liu , Heng Dong , Xing-Jie Liang , Yuan Huang
- Military Medical Research Vol. 13, Issue 2, Pages: 284-328(2026)
- Affiliations：
  1.Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Research Institute of Stomatology, Nanjing University, Nanjing 210008, China
  2.Department of Gastroenterology and Hepatology and Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China
  3.Department of Obstetrics and Gynecology, Renmin Hospital of Wuhan University, Wuhan 430060, China
  4.Department of Immunology, Hebei Medical University, Shijiazhuang 050017, China
  5.Department of Immunology, Binzhou Medical University, Yantai 264100, Shandong, China
  6.Hypertension Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
  7.Department of Chemical Engineering, Tsinghua University, Beijing 100084, China
  8.Hepato-Pancreato-Biliary Center, Beijing Tsinghua Changgung Hospital, & Key Laboratory of Digital Intelligence Hepatology, Ministry of Education, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing 102218, China
  9.CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing 100190, China
  10.State Key Laboratory of New Pharmaceutical Preparations and Excipients, Hebei University, Baoding 071000, Hebei, China
  11.School of Biomedical Engineering, Guangzhou Medical University, Guangzhou 511436, China
  12.Department of Structural Heart Disease, National Center for Cardiovascular Disease, China/Fuwai Hospital, Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing 100037, China
- Author bio：
  * Juan Liu Lja02720@btch.edu.cn
  Heng Dong dongheng90@smail.nju.edu.cn
  Xing-Jie Liang liangxj@nanoctr.cn
  Yuan Huang clevelandhuangyuan@163.com
- Funds：
- DOI： 10.1186/s40779-025-00664-6
  CLC：
- Accepted：26 October 2025 ，
- Accepted：
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Engineered immune-driven theranostics for clinical cardiology

DOI： 10.1186/s40779-025-00664-6

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