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Diagnostic efficacy of fecal-based miR-92a for advanced colorectal neoplasia: a prospective multicenter screening trial
RESEARCH | Updated:2026-01-27
    • Diagnostic efficacy of fecal-based miR-92a for advanced colorectal neoplasia: a prospective multicenter screening trial

    • In a prospective multicenter screening trial, miR-92a demonstrated better sensitivity, NNS, Youden index and AUC as compared with FIT for advanced colorectal neoplasia screening. Using miR-92a appears to be more efficient for population-based screening programs, and screening sensitivity can be further enhanced if conditionally used in combination with FIT.
    • Military Medical Research   Vol. 12, Issue 11, Pages: 1722-1734(2025)
    • DOI:10.1186/s40779-025-00613-3    

      CLC:
    • Received:02 January 2025

      Accepted:29 April 2025

      Online First:13 June 2025

      Published:2025-11

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  • Jia-Chen Wang, Li Zhao, Xiang-Yang Yu, et al. Diagnostic efficacy of fecal-based miR-92a for advanced colorectal neoplasia: a prospective multicenter screening trial[J]. Military Medical Research, 2025, 12(11): 1722-1734. DOI: 10.1186/s40779-025-00613-3.

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