Your Location：
Home >
Browse articles >
Diagnostic efficacy of fecal-based miR-92a for advanced colorectal neoplasia: a prospective multicenter screening trial
RESEARCH | Updated：2026-01-27
Previous|Next

    • Diagnostic efficacy of fecal-based miR-92a for advanced colorectal neoplasia: a prospective multicenter screening trial

    • “In a prospective multicenter screening trial, miR-92a demonstrated better sensitivity, NNS, Youden index and AUC as compared with FIT for advanced colorectal neoplasia screening. Using miR-92a appears to be more efficient for population-based screening programs, and screening sensitivity can be further enhanced if conditionally used in combination with FIT.”
    • Jia-Chen Wang , Li Zhao , Xiang-Yang Yu , Ting-Ping Wu , Chang-Fa Xia , Ju-Fang Shi , Hui He , Zhi-Qi Chen , Dan Shi , Han Xue , Qi Ao , Shu-Ping Liao , Zhang-Qiang Zheng , Qiong-Fang Huang , Lin Li , Sui-Ling Lin , Ying-Xue Li , Wen-Long Hu , Ji Peng , Lin Lei , Mao-Mao Cao , Fan Yang , Xin-Xin Yan , Si-Yi He , Meng-Di Cao , Shao-Li Zhang , Yi Teng , Qian-Ru Li , Nuo-Pei Tan , Hao-Yang Yu , Hong-Hui Cheng , Xi-Mo Wang , Wei-Qing Wu , Wan-Qing Chen
    • Military Medical Research Vol. 12, Issue 11, Pages: 1722-1734(2025)

    • DOI： 10.1186/s40779-025-00613-3     

      CLC：

    • Accepted：29 April 2025 ，

    Scan QR Code

  •  
  •  

  • AI Introduction

  • Full Text(HTML)

  • Figs( 2 ) Tabs( 3 )

  • References

  • Publication Info

  • Metrics

99

Views

35

Downloads

0

CSCD

Alert me when the article has been cited
Submit
Tools
  • BibTeXDownload
  • EndnoteDownload
  • RefMan Download
  • NoteExpressDownload
  • NoteFirstDownload

Related Articles

Effectiveness and cost-effectiveness of risk-adapted colorectal cancer screening: a randomized controlled trial and modeling analysis
Molecular diagnostic approaches for enteric parasites: an issue of relevance for deployed soldiers?
Bridging the lung cancer screening eligibility gap: evaluation of guideline applicability in asymptomatic patients
Engineered exosomes for diabetic foot ulcers: lessons learned, challenges remain
Octopus-inspired engineered bacteria with a plug-and-play surface display system achieves enhanced tumor-specific colonization and antitumor immunity

Related Author

Hong-Hui Cheng
Xi-Mo Wang
Wei-Qing Wu
Wan-Qing Chen
Hong-Da Chen
Bin Lu
Ju-Fang Shi
Yue-Yang Zhou

Related Institution

German Cancer Con-sortium (DKTK), German Cancer Research Center (DKFZ)
Center for Prevention and Early Intervention, National Infrastructures for Translational Medicine, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Department of Cancer Epidemiol-ogy, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Office of Cancer Screening, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Department of Cancer Prevention, Institute of Cancer and Basic Medicine (ICBM), Chinese Academy of Sciences, Cancer Hospital of University of Chinese Academy of Sciences, Zhejiang Cancer Hospital