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TGF-β1 mediates hypoxia-preconditioned olfactory mucosa mesenchymal stem cells improved neural functional recovery in Parkinson’s disease models and patients
RESEARCH | Updated：2025-12-13
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    • TGF-β1 mediates hypoxia-preconditioned olfactory mucosa mesenchymal stem cells improved neural functional recovery in Parkinson’s disease models and patients

    • “In the field of Parkinson's disease treatment, researchers have made significant progress. They found that transforming growth factor-β1 (TGF-β1) secreted from hypoxia-preconditioned olfactory mucosa-mesenchymal stem cells (hOM-MSCs) plays a critical role in modulating mitochondrial function recovery in dopaminergic neurons, providing a new direction for PD research.”
    • Yi Zhuo , Wen-Shui Li , Wen Lu , Xuan Li , Li-Te Ge , Yan Huang , Qing-Tao Gao , Yu-Jia Deng , Xin-Chen Jiang , Zi-Wei Lan , Que Deng , Yong-Heng Chen , Yi Xiao , Shuo Lu , Feng Jiang , Zuo Liu , Li Hu , Yu Liu , Yu Ding , Zheng-Wen He , De-An Tan , Da Duan , Ming Lu
    • Military Medical Research Vol. 12, Issue 5, Pages: 686-715(2025)

    • DOI： 10.1186/s40779-024-00550-7     

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