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CRISPR/Cas9 nickase mediated signal amplification integrating with the trans-cleavage activity of Cas12a for highly selective and sensitive detection of single base mutations
LETTER TO THE EDITOR | Updated：2025-12-13
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    • CRISPR/Cas9 nickase mediated signal amplification integrating with the trans-cleavage activity of Cas12a for highly selective and sensitive detection of single base mutations

    • “In the field of xxx, expert xx has made significant progress. They established the xx system/explored the xx topic/verified the xx conjecture, offering solutions to tackle xx problems and paving the way for future research in xx.”
    • Xiao-Wen Fan , Zi-Fan Gao , Dong-Dong Ling , De-Hui Wang , Ying Cui , Hui-Qun Du , Chun-Lin Li , Xing Zhou
    • Military Medical Research Vol. 12, Issue 5, Pages: 803-806(2025)

    • DOI： 10.1186/s40779-024-00530-x     

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