In situ genetic engineering of host T-cells based on acellular scaffold strategy: a big but also small step for solid tumor immunotherapy

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In situ genetic engineering of host T-cells based on acellular scaffold strategy: a big but also small step for solid tumor immunotherapy

COMMENTARY | Updated：2025-12-13

- In situ genetic engineering of host T-cells based on acellular scaffold strategy: a big but also small step for solid tumor immunotherapy
- “In the field of xxx, expert xx has made significant research progress. By establishing the xx system/exploring the xx topic/verifying the xx conjecture, xx has provided solutions to address xx problems/open up a new direction for xx research/lay a foundation for the construction of the xx system.”
- Shu-Yan Han , Zi-Xuan Zhao , Jun Wu
- Military Medical Research Vol. 12, Issue 4, Pages: 636-638(2025)
- Affiliations：
  1.Bioscience and Biomedical Engineering Thrust, the Hong Kong University of Science and Technology (Guangzhou), Guangzhou 511400, China
  2.Department of Nephrology, Center of Kidney and Urology, the Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen 518107, Guangdong, China
  3.Division of Life Science, the Hong Kong University of Science and Technology, Hong Kong 999077, China
- Author bio：
  *junwuhkust@ust.hk
- Funds：
- DOI： 10.1186/s40779-024-00517-8
  CLC：
- Accepted：
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