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Acellular scaffold-based approach for in situ genetic engineering of host T-cells in solid tumor immunotherapy
Acellular scaffold-based approach for
in situ genetic engineering of host T-cells in solid tumor immunotherapy- “Targeted T-cell therapy has made significant progress in treating hematological malignancies, but faces challenges in solid tumors. Experts have developed a polyethylene glycol-based 3D scaffold system, which provides an innovative in situ localized approach for programming T-cells to target solid tumors, offering a viable alternative to in vitro manipulation of T-cells.”
- Military Medical Research Vol. 12, Issue 1, Pages: 16-35(2025)
DOI： 10.1186/s40779-023-00503-6
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Related Author
Shu-Yan Han
Zi-Xuan Zhao
Jun Wu
Related Institution
Bioscience and Biomedical Engineering Thrust, the Hong Kong University of Science and Technology
Department of Nephrology, Center of Kidney and Urology, the Seventh Affiliated Hospital of Sun Yat-sen University
Division of Life Science, the Hong Kong University of Science and Technology
