Apoptosis-resistant megakaryocytes produce large and hyperreactive platelets in response to radiation injury

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Apoptosis-resistant megakaryocytes produce large and hyperreactive platelets in response to radiation injury

RESEARCH | Updated：2025-12-13

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- Apoptosis-resistant megakaryocytes produce large and hyperreactive platelets in response to radiation injury
- “A new study introduces its research progress in the field of thrombocytopenia. Experts established a mouse model of radiation injury-induced thrombocytopenia and explored the underlying pathogenic mechanism, which provides solutions to solve thrombosis problems.”
- Chang-Hong Du , Yi-Ding Wu , Ke Yang , Wei-Nian Liao , Li Ran , Chao-Nan Liu , Shu-Zhen Zhang , Kuan Yu , Jun Chen , Yong Quan , Mo Chen , Ming-Qiang Shen , Hong Tang , Shi-Lei Chen , Song Wang , Jing-Hong Zhao , Tian-Min Cheng , Jun-Ping Wang
- Military Medical Research Vol. 11, Issue 6, Pages: 797-817(2024)
- Affiliations：
  1.State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Army Medical University, Chongqing 400038, China
  2.Frontier Medical Training Brigade, Army Medical University, Hutubi 831200, Xinjiang, China
  3.Department of Nephrology, the Key Laboratory for the Prevention and Treatment of Chronic Kidney Disease of Chongqing, Kidney Center of PLA, Xinqiao Hospital, Army Medical University, Chongqing 400037, China
- Author bio：
  *changhongdu@tmmu.edu.cn;
  wangjunping@tmmu.edu.cn
- Funds：
- DOI： 10.1186/s40779-023-00499-z
  CLC：
- Accepted：
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