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Adipsin inhibits Irak2 mitochondrial translocation and improves fatty acid β-oxidation to alleviate diabetic cardiomyopathy
RESEARCH | Updated:2025-12-13
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    • Adipsin inhibits Irak2 mitochondrial translocation and improves fatty acid β-oxidation to alleviate diabetic cardiomyopathy

    • “In the field of diabetic cardiomyopathy, researchers have made significant progress. They found that Adipsin improves fatty acid β-oxidation and alleviates mitochondrial injury in DCM, with the mechanism related to Irak2 interaction and inhibition of Irak2 mitochondrial translocation.”
    • Meng-Yuan Jiang , Wan-Rong Man , Xue-Bin Zhang , Xiao-Hua Zhang , Yu Duan , Jie Lin , Yan Zhang , Yang Cao , De-Xi Wu , Xiao-Fei Shu , Lei Xin , Hao Wang , Xiao Zhang , Cong-Ye Li , Xiao-Ming Gu , Xuan Zhang , Dong-Dong Sun
    • Military Medical Research Vol. 11, Issue 5, Pages: 625-642(2024)
    • DOI: 10.1186/s40779-023-00493-5     

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