Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice

Yun-Meng Bai; Fan Yang; Piao Luo; Lu-Lin Xie; Jun-Hui Chen; Yu-Dong Guan; Hong-Chao Zhou; Teng-Fei Xu; Hui-Wen Hao; Bing Chen; Jia-Hui Zhao; Cai-Ling Liang; Ling-Yun Dai; Qing-Shan Geng; Ji-Gang Wang

doi:10.1186/s40779-023-00441-3

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Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice

RESEARCH | Updated：2024-01-23

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- Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice
- “On January 23, 2024, a team of experts led by Yun-Meng Bai, Ling-Yun Dai, Qing-Shan Geng, Ji-Gang Wang from the School of Department of Nephrologypublished an article in the MMR, introduces its research progress in the field of triclosan-induced liver fibrosis. The team established a single-cell atlas of TCS-exposed mouse livers, revealing key cellular and molecular mechanisms driving hepatotoxicity, which provides solutions to solve environmental pollutant-related liver disease problems.”
- Yun-Meng Bai , Fan Yang , Piao Luo , Lu-Lin Xie , Jun-Hui Chen , Yu-Dong Guan , Hong-Chao Zhou , Teng-Fei Xu , Hui-Wen Hao , Bing Chen , Jia-Hui Zhao , Cai-Ling Liang , Ling-Yun Dai , Qing-Shan Geng , Ji-Gang Wang
- Military Medical Research Vol. 10, Issue 5, Pages: 599-619(2023)
- Affiliations：
  1.Department of Nephrology, Shenzhen Key Laboratory of Kidney Diseases, and Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People’s Hospital, the First Affiliated Hospital, Southern University of Science and Technology, Shenzhen 518020, China
  2.Department of Urology, Shenzhen People’s Hospital, the First Affiliated Hospital, Southern University Science and Technology, the Second Clinical Medical College, Jinan University, Shenzhen 518020, China
  3.Integrated Chinese and Western Medicine Postdoctoral Research Station, Jinan University, Guangzhou 510632, China
  4.Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China
  5.Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China
  6.Center for Reproductive Medicine, Dongguan Maternal and Child Health Care Hospital, Southern Medical University, Dongguan 523125, Guangdong, China
- Author bio：
  * dai.lingyun@szhospital.com;
  gengqingshan@gdph.org.cn;
  jgwang@icmm.ac.cn
- Funds：
- DOI： 10.1186/s40779-023-00441-3
  CLC：
- Accepted：
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Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice

DOI： 10.1186/s40779-023-00441-3

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