Activated Drp1 regulates p62-mediated autophagic flux and aggravates inflammation in cerebral ischemia-reperfusion via the ROS-RIP1/RIP3-exosome axis

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Activated Drp1 regulates p62-mediated autophagic flux and aggravates inflammation in cerebral ischemia-reperfusion via the ROS-RIP1/RIP3-exosome axis

RESEARCH | Updated：2023-03-20

- Activated Drp1 regulates p62-mediated autophagic flux and aggravates inflammation in cerebral ischemia-reperfusion via the ROS-RIP1/RIP3-exosome axis
- Xue Zeng , Yun-Dong Zhang , Rui-Yan Ma , Yuan-Jing Chen , Xin-Ming Xiang , Dong-Yao Hou , Xue-Han Li , He Huang , Tao Li , Chen-Yang Duan
- Military Medical Research Vol. 9, Issue 6, Pages: 668-685(2022)
- Affiliations：
  1.Department of Anaesthesiology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China
  2.Department of Neurology, the Third Affiliated Hospital of Chongqing Medical University, Chongqing 401120, China
  3.Department of Cardiovascular Surgery, Xinqiao Hospital, Army Medical University, Chongqing 400037, China
  4.State Key Laboratory of Trauma, Burns and Combined Injury, Department of Shock and Transfusion, Daping Hospital, Army Medical University, Chongqing 400042, China
- Author bio：
  * 13708385559@163.com;
  lt200132@126.com;
  duanchenyang1991@cqmu.edu.cn
- Funds：
- DOI： 10.1186/s40779-022-00383-2
  CLC：
- Accepted：
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