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From nerve to bone: a tale of autonomic nervous system, bone cells, and beyond
From nerve to bone: a tale of autonomic nervous system, bone cells, and beyond
- “Research reveals the autonomic nervous system precisely regulates bone metabolism via neurotransmitters, modulating stem cells, osteoblasts and osteoclasts. Experts established the ANS-bone axis framework, exploring targeted neuromodulation therapies for osteoporosis, osteoarthritis and fractures, which opens up a new direction for musculoskeletal disease treatment.”
- Military Medical Research (2026)
DOI: 10.1016/j.mmr.2026.100051
Accepted:23 June 2026
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Related Author
Ren-Fang Mao
Yang Lu
Yi-Yu Shi
Yong-Lin Chen
De-Cao Ma
Xing-Juan Li
Yan-Hong Jiang
Qian-Qian Liu
Related Institution
Department of Pathophysiology, School of Medicine, Nantong University
Department of Critical Care, Affiliated Hospital of Nantong University
Department of Pathology, the First Hospital of Lanzhou University
Institute of Cancer Neuroscience, Medical Frontier Innovation Research Center, the First Hospital of Lanzhou University, the First Clinical Medical College of Lanzhou University
State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Tianjin Key Laboratory of Gene Therapy for Blood Diseases, CAMS Key Laboratory of Gene Therapy for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

