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Sepsis bei Verbrennungen: gelernte Lektionen, verbleibende Herausforderungen

  • role： Corresponding author, First author通信作者, 第一作者
  • Affiliation：

    Department of Hand Surgery, Plastic Surgery, and Burns, Linköping University, 581 85 Linköping, Sweden

    Department of Biomedical and Clinical Sciences, Linköping University, 581 85 Linköping, Sweden

  • Email：folke.sjoberg@liu.se
  • Introduction：* Folke Sjöberg folke.sjoberg@liu.se
Folke Sjöberg12*,  
  • Affiliation：

    Department of Burns, Shriners Children’s Northern California and Department of Surgery, University of California, Davis, Sacramento, CA 95817-2215, USA

David Greenhalgh3,  
  • Affiliation：

    Department of Hand Surgery, Plastic Surgery, and Burns, Linköping University, 581 85 Linköping, Sweden

    Department of Biomedical and Clinical Sciences, Linköping University, 581 85 Linköping, Sweden

Moustafa Elmasry12,  
  • Affiliation：

    Department of Biomedical and Clinical Sciences, Linköping University, 581 85 Linköping, Sweden

    Medical Laboratory Science Department, College of Health Sciences, University of Sharjah, 27272, Sharjah, United Arab Emirates

Ahmed T. El-Serafi24,  
  • Affiliation：

    Department of Hand Surgery, Plastic Surgery, and Burns, Linköping University, 581 85 Linköping, Sweden

    Department of Biomedical and Clinical Sciences, Linköping University, 581 85 Linköping, Sweden

Ingrid Steinvall12

Resümee

Schlüsselwort

Verbrennungsverletzung;Sepsis;Epidemiologie;Biomarker;Künstliche Intelligenz;Antibiotika

References

  1. 1..
    Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016;315(8):801–10.
  2. 2..
    Greenhalgh DG, Hill DM, Burmeister DM, Gus EI, Cleland H, Padiglione A,et al. Surviving sepsis after burn campaign. Burns. 2023;49(7):1487–524.
  3. 3..
    Bergquist M, Hastbacka J, Glaumann C, Freden F, Huss F, Lipcsey M. The time-course of the inflammatory response to major burn injury and its relation to organ failure and outcome. Burns. 2019;45(2):354–63.
  4. 4..
    Sjöberg F, Greenhalgh D, Elmasry M, Abdelrahman I, El-Serafi AT, Steinvall I. High early incidence of sepsis and its impact on organ dysfunction in burn trauma patients: a detailed and hypothesis generating study. Burns Trauma. 2025;13:tkae085.
  5. 5..
    Knuth CM, Rehou S, Barayan D, Jeschke MG. Evaluating sepsis criteria in detecting alterations in clinical, metabolic, and inflammatory parameters in burn patients. Shock. 2022;58(1):103–10.
  6. 6..
    Yoon J, Kym D, Hur J, Cho YS, Chun W, Yoon D. Validation of Sepsis-3 using survival analysis and clinical evaluation of quick SOFA, SIRS, and burn-specific SIRS for sepsis in burn patients with suspected infection. PLoS One. 2023;18(1):e0276597.
  7. 7..
    Tedesco DJ, Hutter MF, Khalaf F, Ricciuti Z, Jeschke MG. Sepsis in burn care: incidence and outcomes. Mil Med Res. 2025;12(1):55.

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