The "cytokine storm" in infection and sepsis:win the battle but lose the war

Jiang-Bo Fan; Qin-Yuan Li; Xi-Feng Feng; Si-Yuan Huang; Rui Wang; Feng-Ying Liao; Di Liu; Wen-Yi Liu; Jian-Hui Sun; Hua-Cai Zhang; Hui-Ting Zhou; Jian-Xin Jiang; Zhen Wang; Ling Zeng

doi:10.1186/s40779-025-00678-0

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The "cytokine storm" in infection and sepsis:win the battle but lose the war

REVIEW | 更新时间：2026-06-10

- The "cytokine storm" in infection and sepsis:win the battle but lose the war
- The "cytokine storm" in infection and sepsis:win the battle but lose the war
- “On June 10, 2026, a team of experts led by Jiang-Bo Fan, Jian-Xin Jiang, Ling Zeng from the School of Department of Trauma Medical CenterandZhen Wang from the School of Department of Critical Care Medicinepublished an article in the MMR, explores cytokine storm mechanisms in severe infections and potential therapies including cytokine antagonists and JAK inhibitors, providing solutions to reduce multiorgan failure mortality.”
- Jiang-Bo Fan ，Qin-Yuan Li ，Xi-Feng Feng ，Si-Yuan Huang ，Rui Wang ，Feng-Ying Liao ，Di Liu ，Wen-Yi Liu ，Jian-Hui Sun ，Hua-Cai Zhang ，Hui-Ting Zhou ，Jian-Xin Jiang ，Zhen Wang ，Ling Zeng
- Military Medical Research 2026年13卷第5期页码：811-832
- 作者机构：
  1.Department of Trauma Medical Center, Daping Hospital, State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing 400042, China
  2.Department of Respiratory Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Children and Adolescents’Health and Diseases, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Rare Diseases in Infection and Immunity, Chongqing 400014, China
  3.Institute of Pediatric Research, Children’s Hospital of Soochow University, Suzhou 215025, Jiangsu, China
  4.Department of Critical Care Medicine, State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University, Chongqing 400042, China
- 作者简介：
  * Jian-Xin Jiang hellojjx@tmmu.edu.cn
  Zhen Wang dpicuwz@tmmu.edu.cn
  Ling Zeng zengling_1025@tmmu.edu.cn
- 基金信息：
  the National Natural Science Foundation of China(82222038;81970259;82502606);the Outstanding Youth in National Defense Science and Technology(2023-JCJQ-ZQ-001);the Outstanding Young Talents of National Defense Biotechnology(01-SWKJYCJJ06);the Chongqing Outstanding Youth Fund(CSTB2022NSCQ-JQX0017);the Military Clinical Key Specialty Construction Project, and the Chongqing Municipal Postdoctoral Research Project Special Funding Program(2024CQBSHTB2010)
- DOI： 10.1186/s40779-025-00678-0
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- 录用：2025-11-24 ，
- 稿件说明：
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The "cytokine storm" in infection and sepsis:win the battle but lose the war

The "cytokine storm" in infection and sepsis:win the battle but lose the war

DOI： 10.1186/s40779-025-00678-0

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