Effectiveness and cost-effectiveness of risk-adapted colorectal cancer screening: a randomized controlled trial and modeling analysis

Hong-Da Chen; Bin Lu; Ju-Fang Shi; Yue-Yang Zhou; Ling-Bin Du; Xian-Zhen Liao; Dong-Hua Wei; Dong Dong; Yi Gao; Chen Zhu; Rong-Biao Ying; Wei-Fang Zheng; Shi-Peng Yan; Hai-Fan Xiao; Juan Zhang; Yun-Xin Kong; Fu-Rong Li; Na Li; Jia-Hui Luo; Chen-Yu Luo; Hermann Brenner; Min Dai

doi:10.1186/s40779-025-00671-7

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Effectiveness and cost-effectiveness of risk-adapted colorectal cancer screening: a randomized controlled trial and modeling analysis

RESEARCH | 更新时间：2026-08-20

- Effectiveness and cost-effectiveness of risk-adapted colorectal cancer screening: a randomized controlled trial and modeling analysis
- Effectiveness and cost-effectiveness of risk-adapted colorectal cancer screening: a randomized controlled trial and modeling analysis
- Hong-Da Chen ，Bin Lu ，Ju-Fang Shi ，Yue-Yang Zhou ，Ling-Bin Du ，Xian-Zhen Liao ，Dong-Hua Wei ，Dong Dong ，Yi Gao ，Chen Zhu ，Rong-Biao Ying ，Wei-Fang Zheng ，Shi-Peng Yan ，Hai-Fan Xiao ，Juan Zhang ，Yun-Xin Kong ，Fu-Rong Li ，Na Li ，Jia-Hui Luo ，Chen-Yu Luo ，Hermann Brenner ，Min Dai
- Military Medical Research 2026年13卷第6期页码：881-893
- 作者机构：
  Center for Prevention and Early Intervention, National Infrastructures for Translational Medicine, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
  Department of Cancer Epidemiol-ogy, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
  Office of Cancer Screening, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
  Department of Cancer Prevention, Institute of Cancer and Basic Medicine (ICBM), Chinese Academy of Sciences, Cancer Hospital of University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou 310022, China
  Department of Cancer Prevention, Hunan Cancer Hospital, Changsha 410013, China
  Department of Cancer Prevention, Anhui Provincial Cancer Hospital, Hefei 230031, China
  Office of Cancer Preven-tion and Treatment, Xuzhou Cancer Hospital, Xuzhou 221005, Jiangsu, China
  Department of Colorectum Surgery, Tumor Hospital of Yunnan Province, Third Affiliated Hospital of Kunming Medical University, Kunming 650118, China
  Department of Surgical Oncology, Taizhou Cancer Hospital, Taizhou 317502, Zhejiang, China
  Department of Anorectal Diseases, Lanxi Hospital of Tradi-tional Chinese Medicine, Jinhua 321100, Zhejiang, China
  Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Baden-Württemberg, Germany
  German Cancer Con-sortium (DKTK), German Cancer Research Center (DKFZ), 69120 Heidelberg, Baden-Württemberg, Germany
- 作者简介：
  * Hong-Da Chen chenhongda@pumch.cn
  Min Dai daimin2002@hotmail.com
- 基金信息：
  the Chinese Academy of Medical Science Innova-tion Fund for Medical Science(2022-I2M-1-003);the National Natural Science Foundation of China(82173606;82273726);the Beijing Nova Program of Science and Technology(20230484397)
- DOI： 10.1186/s40779-025-00671-7
  中图分类号：
- 录用：2025-11-04 ，
- 稿件说明：
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