Neurogenic organ dysfunction syndrome after acute brain injury

Heng Zhang; Wen-Jin Chen; Yan-Gong Chao; Nan Su; Chiara Robba; Marek Czosnyka; Peter Smielewski; Zofia Czosnyka; Wei He; Xiao Hu; De-Zhong Yao; Cheng-Gong Hu; Min Zhou; Yun-Jie Wang; Xiao-Chun Ma; Xiu-Yun Liu; Dong Ming

doi:10.1186/s40779-025-00662-8

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Neurogenic organ dysfunction syndrome after acute brain injury

PERSPECTIVE | 更新时间：2026-06-10

- Neurogenic organ dysfunction syndrome after acute brain injury
- Neurogenic organ dysfunction syndrome after acute brain injury
- “研究人员引入了新的术语神经源性器官功能障碍综合征（NODS）来描述急性脑损伤后的系统不稳定。他们从复杂脑网络理论中探索了NODS机制，重点研究了中枢自主神经系统的结构网络和中枢应激系统的功能网络。这为早期发现和预防并发症提供了解决方案，改善了患者的预后。”
- Heng Zhang ，Wen-Jin Chen ，Yan-Gong Chao ，Nan Su ，Chiara Robba ，Marek Czosnyka ，Peter Smielewski ，Zofia Czosnyka ，Wei He ，Xiao Hu ，De-Zhong Yao ，Cheng-Gong Hu ，Min Zhou ，Yun-Jie Wang ，Xiao-Chun Ma ，Xiu-Yun Liu ，Dong Ming
- Military Medical Research 2026年13卷第4期页码：542-558
- 作者机构：
  1.Department of Neurosurgery, the First Hospital of China Medical University, Shenyang 110001, China
  2.Department of Neurosurgery, Neuroscience ICU, Xuanwu Hospital Capital Medical University, Beijing 100032, China
  3.Depart-ment of Critical Care Medicine, the First Hospital of Tsinghua University, Beijing 100016, China
  4.State Key Laboratory of Advanced Medical Materials and Devices, School of Medicine, Tianjin University, Tianjin 300072, China
  5.IRCCS for Oncology and Neuroscience, San Martino Policlinico Hospital, 16132 Genoa, Italy
  6.Department of Clinical Neurosciences, University of Cambridge, Cambridge CB1 0QQ, UK
  7.Department of Critical Care Medicine, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
  8.Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA 30322, USA
  9.Ministry of Education Key Laboratory for Neuroinformation, School of Life Science and Technology, University of Electronic Science and Technology, Chengdu 611731, China
  10.Department of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041, China
  11.Department of Critical Care Medicine, the First Affiliated Hospital of USTC, Division of Life Science and Medicine, University of Science and Technology of China, Hefei 230001, China
  12.Department of Critical Care Medicine, the First Hospital of China Medical University, Shenyang 110001, China
  13.Haihe Laboratory of Brain-Computer Interaction and Human-Machine Integration, Tianjin 300380, China
  14.School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China
- 作者简介：
  * Yun-Jie Wang 19721015@cmu.edu.cn
  Xiao-Chun Ma xcma2972@cmu.edu.cn
  Xiu-Yun Liu xiuyun_liu@tju.edu.cn
  Dong Ming richardming@tju.edu.cn
- 基金信息：
  the Scientific Research Innovation Capability Support Project for Young Faculty(ZYGXQNJSKYCXNLZCXM-H15);the National Science Fund for Excellent Overseas Scholars(0401260011);the National Natural Science Foundation of China(82472098;32300704);the Tianjin Natural Science Foundation—Outstanding Youth Project(24JCJQJC00250);the Major Science and Technology Special Projects and Engineering—Major Project of National Key Laboratories(24ZXZSSS00510);the National Key R&D Program of China(2021YFF1200602);the Non-Profit Central Research Institute Fund of Chinese Academy of Medical Sciences(2024-JKCS-16)
- DOI： 10.1186/s40779-025-00662-8
  中图分类号：
- 录用：2025-10-26 ，
- 稿件说明：
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Neurogenic organ dysfunction syndrome after acute brain injury

Neurogenic organ dysfunction syndrome after acute brain injury

DOI： 10.1186/s40779-025-00662-8

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