Trace element-dictated exosome modules and self-adaptive dual-network hydrogel orchestrate diabetic foot regeneration through complement-mitochondria-autophagy circuitry

Shuang-Qing Wang; Ming-Ji Jin; Ze-Ke Guo; Dong-Ri Shen; Li-Na Jin; Fang Cheng; Yan-Ru Zhao; Teng Liu; Yu-Cai Li; Nuo-Ya Wang; Ling-Qing Chen; Wei Huang; Xiu-Quan Quan; Zhong-Gao Gao

doi:10.1186/s40779-025-00658-4

您当前的位置：

首页 >

文章列表页 >

Trace element-dictated exosome modules and self-adaptive dual-network hydrogel orchestrate diabetic foot regeneration through complement-mitochondria-autophagy circuitry

RESEARCH | 更新时间：2026-06-10

- Trace element-dictated exosome modules and self-adaptive dual-network hydrogel orchestrate diabetic foot regeneration through complement-mitochondria-autophagy circuitry
- Trace element-dictated exosome modules and self-adaptive dual-network hydrogel orchestrate diabetic foot regeneration through complement-mitochondria-autophagy circuitry
- “一个研究小组介绍了其在糖尿病伤口治疗方面的进展。专家们建立了一种具有双网络水凝胶递送的3D微量元素工程外泌体系统，该系统为克服糖尿病足溃疡中的炎症-缺血循环提供了解决方案，并为慢性伤口临床管理奠定了基础。”
- Shuang-Qing Wang ，Ming-Ji Jin ，Ze-Ke Guo ，Dong-Ri Shen ，Li-Na Jin ，Fang Cheng ，Yan-Ru Zhao ，Teng Liu ，Yu-Cai Li ，Nuo-Ya Wang ，Ling-Qing Chen ，Wei Huang ，Xiu-Quan Quan ，Zhong-Gao Gao
- Military Medical Research 2026年13卷第4期页码：559-587
- 作者机构：
  1.State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sci-ences and Peking Union Medical College, Beijing 100050, China
  2.Beijing Key Laboratory of Drug Delivery Technology and Novel Formulations, Department of Pharmaceutics, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
  3.Langfang Kangbao Huitai Biotechnology Co. Ltd, Langfang 065001, Hebei, China
  4.Lan-Jayeon Medical Device Co., Ltd, Beijing 100050, China
  5.Emergency Depart-ment, Yanbian University Hospital, Yanji, Jilin 133000, China
- 作者简介：
  * Zhong-Gao Gao zggao@imm.ac.cn
- 基金信息：
  the Fundamental Research Funds for the Central Universities, Peking Union Medical College(3332025063);the CAMS Innova-tion Fund for Medical Sciences (CIFMS)(2023-I2M-2–006;China);National Natural Science Foundation of China(82073778;82104106)
- DOI： 10.1186/s40779-025-00658-4
  中图分类号：
- 录用：2025-10-02 ，
- 稿件说明：
移动端阅览
DOI：
DOI：

AI导读
HTML全文
图( 8 ) 表( 0 )
参考文献
出版信息
数据统计

56

浏览量

59

下载量

0

CSCD

文章被引用时，请邮件提醒。

提交

工具集

BibTeX下载
Endnote下载
RefMan 下载
NoteExpress下载
NoteFirst下载

关联资源

White-light-induced synthesis of injectable alginate- based composite hydrogels for rapid hemostasis

Octopus-inspired engineered bacteria with a plug-and-play surface display system achieves enhanced tumor-specific colonization and antitumor immunity

Immune microenvironment dynamics in pregnant patients with concomitant autoimmune diseases: mechanisms, challenges, and clinical significance

Bridging the lung cancer screening eligibility gap: evaluation of guideline applicability in asymptomatic patients

Trace element-dictated exosome modules and self-adaptive dual-network hydrogel orchestrate diabetic foot regeneration through complement-mitochondria-autophagy circuitry

Trace element-dictated exosome modules and self-adaptive dual-network hydrogel orchestrate diabetic foot regeneration through complement-mitochondria-autophagy circuitry

DOI： 10.1186/s40779-025-00658-4

AI导读

HTML全文

图( 8 ) 表( 0 )

参考文献

出版信息

数据统计

摘要

Abstract

关键词

Keywords

references