ALDH2 in autophagy and cell death: molecular mechanisms and implications for diseases

Yu Duan; Ze-Chen Shan; Jiao-Jiao Pang; Yu-Guo Chen

doi:10.1186/s40779-025-00646-8

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ALDH2 in autophagy and cell death: molecular mechanisms and implications for diseases

REVIEW | 更新时间：2026-03-26

- ALDH2 in autophagy and cell death: molecular mechanisms and implications for diseases
- ALDH2 in autophagy and cell death: molecular mechanisms and implications for diseases
- “综述了醛脱氢酶2（ALDH2）的研究进展。专家们探索了ALDH2影响自噬和细胞死亡途径的调控机制，为人类疾病治疗提供了一个新的理论框架。”
- Yu Duan ，Ze-Chen Shan ，Jiao-Jiao Pang ，Yu-Guo Chen
- Military Medical Research 2026年13卷第2期页码：239-266
- 作者机构：
  1.Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan 250000, China
  2.Chest Pain Center, Shandong Provincial Clinical Research Center for Emergency and Critical Care Medicine, Institute of Emergency and Critical Care Medicine of Shandong University, Qilu Hospital of Shandong University, Jinan 250000, China
  3.Key Laboratory of Emergency and Critical Care Medicine of Shandong Province, Key Laboratory of Cardiopulmonary-Cerebral Resuscitation Research of Shandong Province, Shandong Provincial Engineering Laboratory for Emergency and Critical Care Medicine, Qilu Hospital of Shandong University, Jinan 250000, China
  4.The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese Ministry of Health and Chinese Academy of Medical Sciences, the State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Qilu Hospital of Shandong University, Jinan 250000, China
- 作者简介：
  * Jiao-Jiao Pang jiaojiaopang@email.sdu.edu.cn
  Yu-Guo Chen chen919085@sdu.edu.cn
- 基金信息：
  the State Key Program of the National Natural Science Foundation of China(82030059);the National Science and Technology Major Project(2023ZD0505501);the National Natural Science Foundation of China(81701952;82172127);the National Key Research and Development Program of China(2020YFC1512700);the Key Research and Development Program of Shandong Province(2021SFGC0503;2022ZLGX03)
- DOI： 10.1186/s40779-025-00646-8
  中图分类号：
- 录用：2025-08-28 ，
- 稿件说明：
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ALDH2 in autophagy and cell death: molecular mechanisms and implications for diseases

ALDH2 in autophagy and cell death: molecular mechanisms and implications for diseases

DOI： 10.1186/s40779-025-00646-8

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