Accelerating cartilage regeneration with DNA-SF hydrogel sustained release system-based cartilage organoids

Cong-Yi Shen; Qi-Rong Zhou; Xiang Wu; Xin-Yu Han; Qin Zhang; Xiao Chen; Yu-Xiao Lai; Long Bai; Ying-Ying Jing; Jian-Hua Wang; Cheng-Long Wang; Zhen Geng; Jia-Can Su

doi:10.1186/s40779-025-00625-z

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Accelerating cartilage regeneration with DNA-SF hydrogel sustained release system-based cartilage organoids

RESEARCH | 更新时间：2026-03-26

- Accelerating cartilage regeneration with DNA-SF hydrogel sustained release system-based cartilage organoids
- Accelerating cartilage regeneration with DNA-SF hydrogel sustained release system-based cartilage organoids
- “介绍软骨修复领域的研究进展。专家们开发了一种DNA丝素蛋白水凝胶缓释系统（DSRGT）来构建软骨类器官（CO）。这一创新策略为解决软骨修复中修复周期延长和效果不佳的问题提供了解决方案。”
- Cong-Yi Shen ，Qi-Rong Zhou ，Xiang Wu ，Xin-Yu Han ，Qin Zhang ，Xiao Chen ，Yu-Xiao Lai ，Long Bai ，Ying-Ying Jing ，Jian-Hua Wang ，Cheng-Long Wang ，Zhen Geng ，Jia-Can Su
- Military Medical Research 2026年13卷第1期页码：1-23
- 作者机构：
  1.Institute of Translational Medicine, Shanghai University, Shanghai 200444, China
  2.MedEng-X Institutes, Shanghai University, Shanghai 200444, China
  3.Organoid Research Center, Shanghai University, Shanghai 200444, China
  4.School of Medicine, Shanghai University, Shanghai 200444, China
  5.National Center for Translational Medicine (Shanghai) SHU Branch, Shanghai University, Shanghai 200444, China
  6.Department of Orthopedics, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China
  7.Centre for Translational Medicine Research and Development, Institute of Bio-medical and Health Engineering, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, Guangdong, China
- 作者简介：
  * Jian-Hua Wang shwangjianhua@gmail.com
  Cheng-Long Wang wangorth@163.com
  Zhen Geng nanboshan1987@163.com
  Jia-Can Su drsujiacan@163.com
- 基金信息：
  the National Key Research and Development Program of China(2022YFB3804300);the Key Project of the National Natural Science Foundation of China(82230071);the National Natural Science Foundation of China(32471395;82427809;82472479);the Shanghai Sci-ence and Technology Innovation Action Plan(23141900600);the Research Physician Training Program of Shanghai Hospital Development Center(SHDC2023CRT013);the Shanghai Municipal Demonstration Project for Innovative Medical Device Applications(23SHS05700)
- DOI： 10.1186/s40779-025-00625-z
  中图分类号：
- 录用：2025-07-03 ，
- 稿件说明：
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Accelerating cartilage regeneration with DNA-SF hydrogel sustained release system-based cartilage organoids

Accelerating cartilage regeneration with DNA-SF hydrogel sustained release system-based cartilage organoids

DOI： 10.1186/s40779-025-00625-z

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