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Diagnostic efficacy of fecal-based miR-92a for advanced colorectal neoplasia: a prospective multicenter screening trial
RESEARCH | 更新时间：2026-01-27
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    • Diagnostic efficacy of fecal-based miR-92a for advanced colorectal neoplasia: a prospective multicenter screening trial

    • Diagnostic efficacy of fecal-based miR-92a for advanced colorectal neoplasia: a prospective multicenter screening trial

    • “在一项前瞻性多中心筛查试验中，与FIT相比，miR-92a在晚期结直肠肿瘤筛查中表现出更好的敏感性、NNS、Youden指数和AUC。使用miR-92a似乎对基于人群的筛查项目更有效，如果有条件地与FIT结合使用，筛查敏感性可以进一步提高。”
    • Jia-Chen Wang ，Li Zhao ，Xiang-Yang Yu ，Ting-Ping Wu ，Chang-Fa Xia ，Ju-Fang Shi ，Hui He ，Zhi-Qi Chen ，Dan Shi ，Han Xue ，Qi Ao ，Shu-Ping Liao ，Zhang-Qiang Zheng ，Qiong-Fang Huang ，Lin Li ，Sui-Ling Lin ，Ying-Xue Li ，Wen-Long Hu ，Ji Peng ，Lin Lei ，Mao-Mao Cao ，Fan Yang ，Xin-Xin Yan ，Si-Yi He ，Meng-Di Cao ，Shao-Li Zhang ，Yi Teng ，Qian-Ru Li ，Nuo-Pei Tan ，Hao-Yang Yu ，Hong-Hui Cheng ，Xi-Mo Wang ，Wei-Qing Wu ，Wan-Qing Chen
    • Military Medical Research 2025年12卷第11期 页码：1722-1734

    • DOI： 10.1186/s40779-025-00613-3     

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    • 录用：2025-04-29 ，

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相关作者

Hong-Hui Cheng
Xi-Mo Wang
Wei-Qing Wu
Wan-Qing Chen
Hong-Da Chen
Bin Lu
Ju-Fang Shi
Yue-Yang Zhou

相关机构

German Cancer Con-sortium (DKTK), German Cancer Research Center (DKFZ)
Center for Prevention and Early Intervention, National Infrastructures for Translational Medicine, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Department of Cancer Epidemiol-ogy, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Office of Cancer Screening, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Department of Cancer Prevention, Institute of Cancer and Basic Medicine (ICBM), Chinese Academy of Sciences, Cancer Hospital of University of Chinese Academy of Sciences, Zhejiang Cancer Hospital