FOXO1 reshapes neutrophils to aggravate acute brain damage and promote late depression after traumatic brain injury

Mi Zhou; Yang-Wu-Yue Liu; Yu-Hang He; Jing-Yu Zhang; Hao Guo; Hao Wang; Jia-Kui Ren; Yi-Xun Su; Teng Yang; Jia-Bo Li; Wen-Hui He; Peng-Jiao Ma; Man-Tian Mi; Shuang-Shuang Dai

doi:10.1186/s40779-024-00523-w

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FOXO1 reshapes neutrophils to aggravate acute brain damage and promote late depression after traumatic brain injury

RESEARCH | 更新时间：2025-12-13

- FOXO1 reshapes neutrophils to aggravate acute brain damage and promote late depression after traumatic brain injury
- FOXO1 reshapes neutrophils to aggravate acute brain damage and promote late depression after traumatic brain injury
- Mi Zhou ，Yang-Wu-Yue Liu ，Yu-Hang He ，Jing-Yu Zhang ，Hao Guo ，Hao Wang ，Jia-Kui Ren ，Yi-Xun Su ，Teng Yang ，Jia-Bo Li ，Wen-Hui He ，Peng-Jiao Ma ，Man-Tian Mi ，Shuang-Shuang Dai
- MMR 2024年11卷第4期页码：521-542
- 作者机构：
  1.Department of Biochemistry and Molecular Biology, School of Basic Medicine, Army Medical University, Chongqing 400038, China
  2.Research Center for Nutrition and Food Safety, Chongqing Key Laboratory of Nutrition and Health, Institute of Military Preventive Medicine, Army Medical University, Chongqing 400038, China
  3.Department of Neurosurgery, Daping Hospital, Army Medical University, Chongqing 400042, China
  4.Department of Trauma and Emergency, Southwest Hospital, Army Medical University, Chongqing 400038, China
  5.Department of Histology and Embryology, Chongqing Key Laboratory of Neurobiology, Brain and Intelligence Research Key Suyixun Laboratory of Chongqing Education Commission, Army Medical University, Chongqing 400038, China
  6.Research Center, Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen 518107, Guangdong, China
- 作者简介：
  Mi Zhou, Yang-Wu-Yue Liu and Yu-Hang He contributed equally to this work
  *mantian_mi@tmmu.edu.cn;
  daiyuyang268@aliyun.com
- 基金信息：
  the National Natural Science Foundation of China(82071779;81901626);the Science Fund for Creative Research Groups of Chongqing Municipal Education Commission of China;the grants from the Talent Foundation of Army Medical University (to Shuang-Shuang Dai);the Scientific Research Grant(ALJ22J003);the Chongqing Natural Science Foundation of China(CSTB2022NSCQ-MSX0177)
- DOI： 10.1186/s40779-024-00523-w
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