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Insights gained from single-cell analysis of chimeric antigen receptor T-cell immunotherapy in cancer
Insights gained from single-cell analysis of chimeric antigen receptor T-cell immunotherapy in cancer
Insights gained from single-cell analysis of chimeric antigen receptor T-cell immunotherapy in cancer
- “嵌合抗原受体（CAR）-T细胞治疗的进展显著改善了复发或难治性血液系统恶性肿瘤患者的临床结果。然而，由于临床效益仅适用于一小部分患者，因此进展仍然受到阻碍。在这篇综述中，我们讨论了CAR-T免疫疗法在临床实践中失败的原因，以及自单细胞测序技术里程碑以来该领域所取得的进展。xx专家建立了xx系统/探索了xx课题/验证了xx猜想，为解决xx问题提供了解决方案/为xx研究开辟了新的方向/为xx系统的建设奠定了基础。”
- MMR 2024年11卷第5期 页码：717-746
DOI： 10.1186/s40779-023-00486-4
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相关作者
Rong-Rong Zhou
Gui-Long Tanzhu
Liu Chen
Jiao-Yang Ning
Gang Xiao
Su Wen
Ce Wang
Hao Wen
相关机构
Xiangya Lung Cancer Center, Xiangya Hospital, Central South University
Department of Neuroscience, West Virginia University School of Medicine, Rockefeller Neuroscience Institute
Department of Pharmaceutical Sciences, West Virginia University School of Pharmacy
Department for BioMedical Research, University of Bern
Department of General Thoracic Surgery, Inselspital, Bern University Hospital, University of Bern
