Prediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia: randomized trials and multiomics analysis

Liang-Kun Guo; Yi Su; Yu-Ya-Nan Zhang; Hao Yu; Zhe Lu; Wen-Qiang Li; Yong-Feng Yang; Xiao Xiao; Hao Yan; Tian-Lan Lu; Jun Li; Yun-Dan Liao; Zhe-Wei Kang; Li-Fang Wang; Yue Li; Ming Li; Bing Liu; Hai-Liang Huang; Lu-Xian Lv; Yin Yao; Yun-Long Tan; Gerome Breen; Ian Everall; Hong-Xing Wang; Zhuo Huang; Dai Zhang; Wei-Hua Yue

doi:10.1186/s40779-023-00459-7

您当前的位置：

首页 >

文章列表页 >

Prediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia: randomized trials and multiomics analysis

RESEARCH | 更新时间：2025-12-13

- Prediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia: randomized trials and multiomics analysis
- Prediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia: randomized trials and multiomics analysis
- Liang-Kun Guo ，Yi Su ，Yu-Ya-Nan Zhang ，Hao Yu ，Zhe Lu ，Wen-Qiang Li ，Yong-Feng Yang ，Xiao Xiao ，Hao Yan ，Tian-Lan Lu ，Jun Li ，Yun-Dan Liao ，Zhe-Wei Kang ，Li-Fang Wang ，Yue Li ，Ming Li ，Bing Liu ，Hai-Liang Huang ，Lu-Xian Lv ，Yin Yao ，Yun-Long Tan ，Gerome Breen ，Ian Everall ，Hong-Xing Wang ，Zhuo Huang ，Dai Zhang ，Wei-Hua Yue
- MMR 2024年11卷第1期页码：19-33
- 作者机构：
  1.Institute of Mental Health, Peking University Sixth Hospital, Beijing 100191, China
  2.National Clinical Research Center for Mental Disorders, Peking University Sixth Hospital, Beijing 100191, China
  3.NHC Key Laboratory of Mental Health and Research Unit of Diagnosis and Treatment of Mood Cognitive Disorder (2018RU006), Chinese Academy of Medical Sciences, Beijing 100191, China
  4.Peking University Huilongguan Clinical Medical School, Beijing Huilongguan Hospital, Beijing 100096, China
  5.Department of Psychiatry, Jining Medical University, Jining 272067, Shandong, China
  6.Henan Key Lab of Biological Psychiatry, the Second Affiliated Hospital of Xinxiang Medical University, Xinxiang 435001, Henan, China
  7.Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China
  8.Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London WC2R 2LS, UK
  9.State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875, China
  10.Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA
  11.Stanley Center for Psychiatric Research, the Broad Institute of MIT and Harvard, Cambridge, MA 02141, USA
  12.Department of Medicine, Harvard Medical School, Boston, MA 02115, USA
  13.Department of Biostatistics and Computational Biology, School of Life Sciences, Fudan University, Shanghai 200438, China
  14.Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
  15.State Key Laboratory of Natural and Biomimetic Drugs, Key Laboratory for Neuroscience for Ministry of Education, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China
  16.PKU-IDG/McGovern Institute for Brain Research, Peking University, Beijing 100871, China
  17.Chinese Institute for Brain Research, Beijing 102206, China
- 作者简介：
  * huangz@hsc.pku.edu.cn;
  daizhang@bjmu.edu.cn;
  dryue@bjmu.edu.cn
- 基金信息：
  grants from the National Natural Science Foundation of China(81825009;82071505;81901358);the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(2021-I2M-C&T-B-099;2019-I2M-5–006);the Program of Chinese Institute for Brain Research Beijing(2020-NKX-XM-12);the King’s College London-Peking University Health Science Center Joint Institute for Medical Research(BMU2020KCL001;BMU2019LCKXJ012);the National Key R&D Program of China(2021YFF1201103;2016YFC1307000)
- DOI： 10.1186/s40779-023-00459-7
  中图分类号：
- 稿件说明：
移动端阅览
DOI：
DOI：

HTML全文
图( 3 ) 表( 2 )
参考文献
出版信息
数据统计

摘要

Abstract

关键词

Keywords

references

82

浏览量

41

下载量

0

CSCD

文章被引用时，请邮件提醒。

提交

工具集

BibTeX下载
Endnote下载
RefMan 下载
NoteExpress下载
NoteFirst下载

关联资源

A prediction model for moderate to severe acute kidney injury in people with heart failure

Amisulpride augmentation therapy improves cognitive performance and psychopathology in clozapine-resistant treatment-refractory schizophrenia: a 12-week randomized, double-blind, placebo-controlled trial

Spine system changes in soldiers after load carriage training in a plateau environment: A prediction model research

Engineered exosomes for diabetic foot ulcers: lessons learned, challenges remain