Amisulpride augmentation therapy improves cognitive performance and psychopathology in clozapine-resistant treatment-refractory schizophrenia: a 12-week randomized, double-blind, placebo-controlled trial

Ming-Huan Zhu; Zhen-Jing Liu; Qiong-Yue Hu; Jia-Yu Yang; Ying Jin; Na Zhu; Ying Huang; Dian-Hong Shi; Min-Jia Liu; Hong-Yang Tan; Lei Zhao; Qin-Yu Lv; Zheng-Hui Yi; Feng-Chun Wu; Ze-Zhi Li

doi:10.1186/s40779-022-00420-0

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Amisulpride augmentation therapy improves cognitive performance and psychopathology in clozapine-resistant treatment-refractory schizophrenia: a 12-week randomized, double-blind, placebo-controlled trial

RESEARCH | 更新时间：2023-09-05

- Amisulpride augmentation therapy improves cognitive performance and psychopathology in clozapine-resistant treatment-refractory schizophrenia: a 12-week randomized, double-blind, placebo-controlled trial
- Amisulpride augmentation therapy improves cognitive performance and psychopathology in clozapine-resistant treatment-refractory schizophrenia: a 12-week randomized, double-blind, placebo-controlled trial
- Ming-Huan Zhu ，Zhen-Jing Liu ，Qiong-Yue Hu ，Jia-Yu Yang ，Ying Jin ，Na Zhu ，Ying Huang ，Dian-Hong Shi ，Min-Jia Liu ，Hong-Yang Tan ，Lei Zhao ，Qin-Yu Lv ，Zheng-Hui Yi ，Feng-Chun Wu ，Ze-Zhi Li
- MMR 2023年10卷第4期页码：431-443
- 作者机构：
  1.Clinical Research Center for Mental Disorders, School of Medicine, Shanghai Pudong New Area Mental Health Center, Tongji University, Shanghai 200124, China
  2.Qingdao Mental Health Center, Qingdao 266034, Shandong, China
  3.Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
  4.Department of Psychiatry, the Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou 510370, China
  5.Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou 510370, China
- 作者简介：
  * 13580380071@163.com;
  biolpsychiatry@126.com
- 基金信息：
  the National Natural Science Foundation of China(81401127);the Clinical Research Project of Shanghai Municipal Health Commission(20204Y0173);the Open Project Program of State Key Laboratory of Virtual Reality Technology and Systems, Beihang University(VRLAB2022 B02);the Shanghai Key Laboratory of Psychotic Disorders Open Grant(21-K03);the Scientific Research Project of Traditional Chinese Medicine of Guangdong(20192070);the Guangzhou Municipal Key Discipline in Medicine(2021–2023);the Science and Technology Plan Project of Guangdong Province(2019B030316001)
- DOI： 10.1186/s40779-022-00420-0
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