Antibacterial efficacy of a chitosan-based hydrogel loaded with epsilon poly-L-lysine and poly(I:C) extracellular vesicles for the control of polymicrobial extremity wound infections in a porcine polytrauma model

Cole E. Ogrydziak; Catherine F.T. Uyehara; Lee-Ann M. Murata; Wendy E. Kurata; Lauren N. Wong; Randal S. Dudis; Emily J. Bailey; Lisa M. Pierce

doi:10.1016/j.mmr.2026.100011

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Antibacterial efficacy of a chitosan-based hydrogel loaded with epsilon poly-L-lysine and poly(I:C) extracellular vesicles for the control of polymicrobial extremity wound infections in a porcine polytrauma model

LETTER TO THE EDITOR | 更新时间：2026-08-20

- Antibacterial efficacy of a chitosan-based hydrogel loaded with epsilon poly-L-lysine and poly(I:C) extracellular vesicles for the control of polymicrobial extremity wound infections in a porcine polytrauma model
- Antibacterial efficacy of a chitosan-based hydrogel loaded with epsilon poly-L-lysine and poly(I:C) extracellular vesicles for the control of polymicrobial extremity wound infections in a porcine polytrauma model
- Cole E. Ogrydziak ，Catherine F.T. Uyehara ，Lee-Ann M. Murata ，Wendy E. Kurata ，Lauren N. Wong ，Randal S. Dudis ，Emily J. Bailey ，Lisa M. Pierce
- 军事医学研究（英文） 2026年13卷第7期页码：1199-1202
- 作者机构：
  Department of General Surgery, Tripler Army Medical Center, Hawaii 96859, USA
  Department of Clinical Investigation, Tripler Army Medical Center, Hawaii 96859, USA
- 作者简介：
  *Lisa M. Pierce, lisa.m.pierce.civ@health.mil
- 基金信息：
  the Department of Clinical Investigation;Tripler Army Medical Center
- DOI： 10.1016/j.mmr.2026.100011
  中图分类号：
- 录用：2026-03-05 ，
- 稿件说明：
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