The cellular response capacity (CRC) as a novel immunomonitoring approach in sepsis

David Alexander Christian Messerer; Paul Müller; Lisa Wohlgemuth; Frederik Münnich; Laura Stukan; Adam Omar Khalaf Mohamed; Jürgen Benjamin Hagemann; Alexander Sebastian Koller; Darko Jovanovski; Simon Lauer; Rebecca Traut; Leonard Schöbel; Bertram Dietrich Thomaß; Finn Münnich; Eberhard Barth; Manfred Weiss; Andreas Liebold; Bettina Jungwirth; Markus Huber-Lang

doi:10.1016/j.mmr.2026.100010

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The cellular response capacity (CRC) as a novel immunomonitoring approach in sepsis

RESEARCH | 更新时间：2026-09-15

- The cellular response capacity (CRC) as a novel immunomonitoring approach in sepsis
- The cellular response capacity (CRC) as a novel immunomonitoring approach in sepsis
- “研究人员开发了中性粒细胞反应能力（CRC），这是一种基于流式细胞术的标准化方法，用于快速检测败血症。专家团队建立了CRC系统，该系统在更早、更精确地检测炎症方面优于IL-6等传统生物标志物，为解决延迟败血症诊断问题提供了解决方案，并为改善重症监护中的免疫监测奠定了基础。”
- David Alexander Christian Messerer ，Paul Müller ，Lisa Wohlgemuth ，Frederik Münnich ，Laura Stukan ，Adam Omar Khalaf Mohamed ，Jürgen Benjamin Hagemann ，Alexander Sebastian Koller ，Darko Jovanovski ，Simon Lauer ，Rebecca Traut ，Leonard Schöbel ，Bertram Dietrich Thomaß ，Finn Münnich ，Eberhard Barth ，Manfred Weiss ，Andreas Liebold ，Bettina Jungwirth ，Markus Huber-Lang
- 军事医学研究（英文） 2026年13卷第8期页码：1222-1241
- 作者机构：
  Institute of Clinical and Experimental Trauma Immunology, University Hospital Ulm, 89081 Ulm, Germany
  Institute of Medical Microbiology and Hygiene, University Hospital Ulm, 89081 Ulm, Germany
  Institute for Transfusion Medicine, University Hospital Ulm, 89081 Ulm, Germany
  Clinic for Cardiothoracic and Vascular Surgery, University Hospital Ulm, 89081 Ulm, Germany
  Clinic for Anesthesiology and Intensive Care Medicine, University Hospital Ulm, 89081 Ulm, Germany
  Anesthesiology and Operative Intensive Care, Faculty of Medicine, University of Augsburg, 86156 Augsburg, Germany
- 作者简介：
  *David Alexander Christian Messerer, david.messerer@uni-ulm.de
- 基金信息：
  a “Gerok Rotation” (rotation as clinician scientist) to DACM, a personal grant to DACM(545061513);project A01(251293561);the German Research Foundation
- DOI： 10.1016/j.mmr.2026.100010
  中图分类号：
- 录用：2026-03-05 ，
- 稿件说明：
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The cellular response capacity (CRC) as a novel immunomonitoring approach in sepsis

The cellular response capacity (CRC) as a novel immunomonitoring approach in sepsis

DOI： 10.1016/j.mmr.2026.100010

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