USP18 exacerbates myocardial I/R injury by inhibiting Parkin mitophagy through the deubiquitinase PTEN-L

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USP18 exacerbates myocardial I/R injury by inhibiting Parkin mitophagy through the deubiquitinase PTEN-L

RESEARCH | 更新时间：2026-08-20

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- USP18 exacerbates myocardial I/R injury by inhibiting Parkin mitophagy through the deubiquitinase PTEN-L
- USP18 exacerbates myocardial I/R injury by inhibiting Parkin mitophagy through the deubiquitinase PTEN-L
- Qing-Qing Wu ，Yang Xiao ，Ying-Ying Hu ，Xiang-Yu Yang ，Xin-Yi Yan ，Ke-Qiong Deng ，Zhi-Li Jin ，Wei Zhang ，Jian-Lei Cao ，Li-Hua Ni ，Yong-Zhen Fan ，Zhi-Bing Lu ，Xiao-Rong Hu
- 军事医学研究（英文） 2026年13卷第7期页码：1102-1122
- 作者机构：
  Department of Cardiology, Zhongnan Hospital of Wuhan University, Wuhan 430062, China
  Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430062, China
  Department of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute, Wuhan University, Wuhan 430060, China
- 作者简介：
  *Zhi-Bing Lu, luzhibing@whu.edu.cn;
  Xiao-Rong Hu, huxrzn@whu.edu.cn
- 基金信息：
  the National Natural Science Foundation of China(82470399;82170382;82400401;82370290);the Wuhan University Zhongnan Hospital Translational Medicine and Interdisciplinary Research Joint Fund(ZNJC202308)
- DOI： 10.1016/j.mmr.2026.100004
  中图分类号：
- 录用：2026-03-05 ，
- 稿件说明：
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