RNA as a genome architect: G-loops in G-quadruplex regulation

Jie Wang; Zhao-Jie Lyu; Qi Zhang; William C. Cho; De-Chao Feng

doi:10.1186/s40779-025-00683-3

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RNA as a genome architect: G-loops in G-quadruplex regulation

COMMENTARY | Updated：2026-01-29

- RNA as a genome architect: G-loops in G-quadruplex regulation
- RNA as a genome architect: G-loops in G-quadruplex regulation
- “在xxx领域，xx专家取得了重大的研究进展。通过建立xx体系/探索xx主题/验证xx猜想，xx为解决xx问题提供了解决方案/为xx研究开辟了新方向/为xx体系的构建奠定了基础。”
- Military Medical Research 2025年12卷
- Affiliations：
  
  1.Urology & Nephrology Center, Department of Urology, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital), Hangzhou Medical College, Hangzhou 310014, China
  2.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China
  3.Department of Urology, Institute of Precision Medicine, Peking University Shenzhen Hospital, Shenzhen, Guangzhou 518036, China
  4.Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong SAR, China
  5.Division of Surgery & Interventional Science, University College London, London W1W 7TS, UK
- Author bio：
  
  * William C. Cho chocs@ha.org.hk
  De-Chao Feng dechao.feng@ucl.ac.uk
- Funds：
  
  the National Health Commission of the People’s Republic of China-Zhejiang Province Jointly Constructed Project, Zhejiang Province Medical and Health Science and Technology Plan(WKJ-ZJ-2517);Clinical-Basic Joint Research Project of Zhejiang Provincial People’s Hospital Affiliated with Hangzhou Medical College(C-2025-YXLH09)
- DOI：10.1186/s40779-025-00683-3
  中图分类号：
- 收稿：2025-10-26，
  
  录用：2025-12-10，
  
  网络首发：2026-01-14，
  
  纸质出版：2025
- Accepted：
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Jie Wang, Zhao-Jie Lyu, Qi Zhang, 等. RNA as a genome architect: G-loops in G-quadruplex regulation[J/OL]. Military Medical Research, 2025,12.

Jie Wang, Zhao-Jie Lyu, Qi Zhang, et al. RNA as a genome architect: G-loops in G-quadruplex regulation[J/OL]. Military Medical Research, 2025, 12.
Jie Wang, Zhao-Jie Lyu, Qi Zhang, 等. RNA as a genome architect: G-loops in G-quadruplex regulation[J/OL]. Military Medical Research, 2025,12. DOI： 10.1186/s40779-025-00683-3.

Jie Wang, Zhao-Jie Lyu, Qi Zhang, et al. RNA as a genome architect: G-loops in G-quadruplex regulation[J/OL]. Military Medical Research, 2025, 12. DOI： 10.1186/s40779-025-00683-3.

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RNA as a genome architect: G-loops in G-quadruplex regulation

RNA as a genome architect: G-loops in G-quadruplex regulation

DOI：10.1186/s40779-025-00683-3