The "cytokine storm" in infection and sepsis:win the battle but lose the war

Jiang-Bo Fan; Qin-Yuan Li; Xi-Feng Feng; Si-Yuan Huang; Rui Wang; Feng-Ying Liao; Di Liu; Wen-Yi Liu; Jian-Hui Sun; Hua-Cai Zhang; Hui-Ting Zhou; Jian-Xin Jiang; Zhen Wang; Ling Zeng

doi:10.1186/s40779-025-00678-0

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The "cytokine storm" in infection and sepsis:win the battle but lose the war

REVIEW | Updated：2026-01-29

- The "cytokine storm" in infection and sepsis:win the battle but lose the war
- The "cytokine storm" in infection and sepsis:win the battle but lose the war
- “细胞因子风暴是一种危及生命的全身炎症综合征，是各种临床情况下多器官衰竭的主要驱动因素。本综述主要关注由病毒性肺炎和细菌性败血症等严重感染引发的细胞因子风暴，探索其潜在机制和潜在的治疗干预措施。xx专家建立了xx系统，为解决xx问题提供了解决方案。”
- Military Medical Research 2025年12卷
- Affiliations：
  
  1.Department of Trauma Medical Center, Daping Hospital, State Key Laboratory of Trauma and Chemical Poisoning, Army Medical University, Chongqing 400042, China
  2.Department of Respiratory Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Children and Adolescents’Health and Diseases, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Rare Diseases in Infection and Immunity, Chongqing 400014, China
  3.Institute of Pediatric Research, Children’s Hospital of Soochow University, Suzhou 215025, Jiangsu, China
  4.Department of Critical Care Medicine, State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University, Chongqing 400042, China
- Author bio：
  
  * Jian-Xin Jiang hellojjx@tmmu.edu.cn
  Zhen Wang dpicuwz@tmmu.edu.cn
  Ling Zeng zengling_1025@tmmu.edu.cn
- Funds：
  
  the National Natural Science Foundation of China(82222038;81970259;82502606);the Outstanding Youth in National Defense Science and Technology(2023-JCJQ-ZQ-001);the Outstanding Young Talents of National Defense Biotechnology(01-SWKJYCJJ06);the Chongqing Science Fund for Distinguished Young Scholars(CSTB2022NSCQ-JQX0017);the Military Clinical Key Specialty Construction Project, and the Chongqing Municipal Postdoctoral Research Project Special Funding Program(2024CQBSHTB2010)
- DOI：10.1186/s40779-025-00678-0
  中图分类号：
- 收稿：2025-08-18，
  
  录用：2025-11-24，
  
  网络首发：2026-01-12，
  
  纸质出版：2025
- Accepted：
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Jiang-Bo Fan, Qin-Yuan Li, Xi-Feng Feng, 等. The "cytokine storm" in infection and sepsis:win the battle but lose the war[J/OL]. Military Medical Research, 2025,12.

Jiang-Bo Fan, Qin-Yuan Li, Xi-Feng Feng, et al. The "cytokine storm" in infection and sepsis:win the battle but lose the war[J/OL]. Military Medical Research, 2025, 12.
Jiang-Bo Fan, Qin-Yuan Li, Xi-Feng Feng, 等. The "cytokine storm" in infection and sepsis:win the battle but lose the war[J/OL]. Military Medical Research, 2025,12. DOI： 10.1186/s40779-025-00678-0.

Jiang-Bo Fan, Qin-Yuan Li, Xi-Feng Feng, et al. The "cytokine storm" in infection and sepsis:win the battle but lose the war[J/OL]. Military Medical Research, 2025, 12. DOI： 10.1186/s40779-025-00678-0.

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The "cytokine storm" in infection and sepsis:win the battle but lose the war

The "cytokine storm" in infection and sepsis:win the battle but lose the war

DOI：10.1186/s40779-025-00678-0