ALDH2 in autophagy and cell death: molecular mechanisms and implications for diseases

Yu Duan; Ze-Chen Shan; Jiao-Jiao Pang; Yu-Guo Chen

doi:10.1186/s40779-025-00646-8

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ALDH2 in autophagy and cell death: molecular mechanisms and implications for diseases

REVIEW | Updated：2026-03-26

- ALDH2 in autophagy and cell death: molecular mechanisms and implications for diseases
- ALDH2 in autophagy and cell death: molecular mechanisms and implications for diseases
- Military Medical Research 2026年13卷第2期页码：239-266
- Affiliations：
  
  1.Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan 250000, China
  2.Chest Pain Center, Shandong Provincial Clinical Research Center for Emergency and Critical Care Medicine, Institute of Emergency and Critical Care Medicine of Shandong University, Qilu Hospital of Shandong University, Jinan 250000, China
  3.Key Laboratory of Emergency and Critical Care Medicine of Shandong Province, Key Laboratory of Cardiopulmonary-Cerebral Resuscitation Research of Shandong Province, Shandong Provincial Engineering Laboratory for Emergency and Critical Care Medicine, Qilu Hospital of Shandong University, Jinan 250000, China
  4.The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese Ministry of Health and Chinese Academy of Medical Sciences, the State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Qilu Hospital of Shandong University, Jinan 250000, China
- Author bio：
  
  * Jiao-Jiao Pang jiaojiaopang@email.sdu.edu.cn
  Yu-Guo Chen chen919085@sdu.edu.cn
- Funds：
  
  the State Key Program of the National Natural Science Foundation of China(82030059);the National Science and Technology Major Project(2023ZD0505501);the National Natural Science Foundation of China(81701952;82172127);the National Key Research and Development Program of China(2020YFC1512700);the Key Research and Development Program of Shandong Province(2021SFGC0503;2022ZLGX03)
- DOI：10.1186/s40779-025-00646-8
  中图分类号：
- 收稿：2025-03-31，
  
  录用：2025-08-28，
  
  网络首发：2025-09-18，
  
  纸质出版：2026-02
- Accepted：
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Yu Duan, Ze-Chen Shan, Jiao-Jiao Pang, 等. ALDH2 in autophagy and cell death: molecular mechanisms and implications for diseases[J]. Military Medical Research, 2026,13(2):239-266.

Yu Duan, Ze-Chen Shan, Jiao-Jiao Pang, et al. ALDH2 in autophagy and cell death: molecular mechanisms and implications for diseases[J]. Military Medical Research, 2026, 13(2): 239-266.
Yu Duan, Ze-Chen Shan, Jiao-Jiao Pang, 等. ALDH2 in autophagy and cell death: molecular mechanisms and implications for diseases[J]. Military Medical Research, 2026,13(2):239-266. DOI： 10.1186/s40779-025-00646-8.

Yu Duan, Ze-Chen Shan, Jiao-Jiao Pang, et al. ALDH2 in autophagy and cell death: molecular mechanisms and implications for diseases[J]. Military Medical Research, 2026, 13(2): 239-266. DOI： 10.1186/s40779-025-00646-8.

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ALDH2 in autophagy and cell death: molecular mechanisms and implications for diseases

ALDH2 in autophagy and cell death: molecular mechanisms and implications for diseases

DOI：10.1186/s40779-025-00646-8