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Diagnostic efficacy of fecal-based miR-92a for advanced colorectal neoplasia: a prospective multicenter screening trial
RESEARCH | Updated：2026-01-27

    • Diagnostic efficacy of fecal-based miR-92a for advanced colorectal neoplasia: a prospective multicenter screening trial

    • Diagnostic efficacy of fecal-based miR-92a for advanced colorectal neoplasia: a prospective multicenter screening trial

    • “在一项前瞻性多中心筛查试验中，与FIT相比，miR-92a在晚期结直肠肿瘤筛查中表现出更好的敏感性、NNS、Youden指数和AUC。使用miR-92a似乎对基于人群的筛查项目更有效，如果有条件地与FIT结合使用，筛查敏感性可以进一步提高。”
    • Military Medical Research   2025年12卷第11期 页码：1722-1734

    • DOI：10.1186/s40779-025-00613-3    

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    • 收稿：2025-01-02，

      录用：2025-04-29，

      网络首发：2025-06-13，

      纸质出版：2025-11

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  • Jia-Chen Wang, Li Zhao, Xiang-Yang Yu, 等. Diagnostic efficacy of fecal-based miR-92a for advanced colorectal neoplasia: a prospective multicenter screening trial[J]. Military Medical Research, 2025,12(11):1722-1734. DOI： 10.1186/s40779-025-00613-3.

    Jia-Chen Wang, Li Zhao, Xiang-Yang Yu, et al. Diagnostic efficacy of fecal-based miR-92a for advanced colorectal neoplasia: a prospective multicenter screening trial[J]. Military Medical Research, 2025, 12(11): 1722-1734. DOI： 10.1186/s40779-025-00613-3.

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相关作者

Hong-Hui Cheng
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相关机构

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Center for Prevention and Early Intervention, National Infrastructures for Translational Medicine, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Department of Cancer Epidemiol-ogy, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Office of Cancer Screening, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
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