Age-stratified associations between radiotherapy and SPMs for FPHNC:a population-based cohort study

Yuan-Yuan Li; Qiong Liu; Si-Qi Ying; Xiu-Quan Wu; Xiao-Hui Zhang; Xiao-Mei Xie; Bing-Dong Sui; Yan Jin; Yang Jiao; Franklin R. Tay

doi:10.1186/s40779-025-00612-4

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Age-stratified associations between radiotherapy and SPMs for FPHNC:a population-based cohort study

RESEARCH | Updated：2026-01-27

- Age-stratified associations between radiotherapy and SPMs for FPHNC:a population-based cohort study
- Age-stratified associations between radiotherapy and SPMs for FPHNC:a population-based cohort study
- “在最近的一项研究中，研究人员调查了癌症患者放疗与第二原发性恶性肿瘤风险之间的年龄相关性。研究结果强调了在做出癌症头部和颈部治疗决定时考虑患者年龄的重要性，并表明长期监测对高危人群是必要的。”
- Military Medical Research 2025年12卷第11期页码：1673-1685
- Affiliations：
  
  1.State Key Laboratory of Oral and Maxillofacial Reconstruction and Regenera-tion, National Clinical Research Center for Oral Diseases, Shaanxi Key Labora-tory of Stomatology, Department of Prosthodontics, School of Stomatology, the Fourth Military Medical University, Xi’an 710032, China
  2.Department of General Dentistry, Xiamen University Affiliated Chenggong Hospital, the 73rd Army Hospital of Chinese PLA, Xiamen 361001, Fujian, China
  3.State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Center for Tissue Engineering, School of Stomatology, the Fourth Military Medical University, Xi’an 710032, China
  4.Department of Orthopedics, Xijing Hospital, the Fourth Military Medical University, Xi’an 710032, China
  5.Department of Neurosurgery, Xijing Hospital, the Fourth Military Medical University, Xi’an 710032, China
  6.State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Clinical Research Center for Oral Diseases, Department of Orthodontics, School of Stomatology, the Fourth Military Medical University, Xi’an 710032, China
  7.Department of Stomatology, the Seventh Medical Center of PLA General Hospital, Beijing 100700, China
  8.Department of Endodontics, the Dental College of Georgia, Augusta University, Augusta, GA 30912-1129, USA
- Author bio：
  
  * Yuan-Yuan Li yuanyuanli1@fmmu.edu.cn
  Yang Jiao jiaoyang1989731@163.com
  Franklin R. Tay ftay@augusta.edu
- Funds：
  
  the National Natural Science Foundation of China(82101069);the Beijing Natural Science Foundation(7242279);the Beijing Nova Program(20230484283);the Beijing Municipal Science & Technology Commission(Z221100007422130);the Open Project of State Key Laboratory of Trauma and Chemical Poisoning(SKLO202401);the Logistics Independ-ent Research Project of PLA(C24LBJ032)
- DOI：10.1186/s40779-025-00612-4
  中图分类号：
- 收稿：2024-12-06，
  
  录用：2025-04-28，
  
  网络首发：2025-05-21，
  
  纸质出版：2025-11
- Accepted：
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Yuan-Yuan Li, Qiong Liu, Si-Qi Ying, 等. Age-stratified associations between radiotherapy and SPMs for FPHNC:a population-based cohort study[J]. Military Medical Research, 2025,12(11):1673-1685.

Yuan-Yuan Li, Qiong Liu, Si-Qi Ying, et al. Age-stratified associations between radiotherapy and SPMs for FPHNC:a population-based cohort study[J]. Military Medical Research, 2025, 12(11): 1673-1685.
Yuan-Yuan Li, Qiong Liu, Si-Qi Ying, 等. Age-stratified associations between radiotherapy and SPMs for FPHNC:a population-based cohort study[J]. Military Medical Research, 2025,12(11):1673-1685. DOI： 10.1186/s40779-025-00612-4.

Yuan-Yuan Li, Qiong Liu, Si-Qi Ying, et al. Age-stratified associations between radiotherapy and SPMs for FPHNC:a population-based cohort study[J]. Military Medical Research, 2025, 12(11): 1673-1685. DOI： 10.1186/s40779-025-00612-4.

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Age-stratified associations between radiotherapy and SPMs for FPHNC:a population-based cohort study

Age-stratified associations between radiotherapy and SPMs for FPHNC:a population-based cohort study

DOI：10.1186/s40779-025-00612-4