Strategies for promoting neurovascularization in bone regeneration

Xin-Ling Li; Yu-Qing Zhao; Li Miao; Yan-Xin An; Fan Wu; Jin-Yu Han; Jing-Yuan Han; Franklin R. Tay; Zhao Mu; Yang Jiao; Jing Wang

doi:10.1186/s40779-025-00596-1

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Strategies for promoting neurovascularization in bone regeneration

REVIEW | Updated：2026-01-27

- Strategies for promoting neurovascularization in bone regeneration
- Strategies for promoting neurovascularization in bone regeneration
- “在骨组织工程领域，本文探讨了骨内血管和神经纤维的解剖和功能，强调了它们在骨发育、代谢和修复中的作用。它涵盖了过去十年中加速骨内神经血管系统的创新策略，为开发新型神经血管化生物材料并加速其转化为临床实践提供了解决方案。”
- Military Medical Research 2025年12卷第11期页码：1747-1781
- Affiliations：
  
  1.State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Oral Implants, School of Stomatology, The Fourth Military Medical University, Xi’an 710032, China
  2.Department of Stomatology, The Seventh Medical Center of PLA General Hospital, Beijing 100700, China
  3.Department of General Surgery, The First Affiliated Hospital of Xi’an Medical University, Xi’an 710077, China
  4.Graduate School of Augusta University, Augusta, GA 30912, USA
  5.State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, School of Stomatology, The Fourth Military Medical University, Xi’an 710032, China
- Author bio：
  
  * Zhao Mu zhaomu1994@126.com
  Yang Jiao jiaoyang1989731@163.com
  Jing Wang jingwang@fmmu.edu.cn
- Funds：
  
  the Foundation of National Clinical Research Center for Oral Diseases(LCA202204);the Key Research and Development Program of Shaanxi(2024GH-YBXM-19);the Clinical New Technology Program of Air Force Medical University(LX2023-306);the China Postdoctoral Science Foundation(2019M653969);the Thousand Talents Plan of Shaanxi Province;the National Natural Science Foundation of China(82101069;22205257);the Logistics Independent Research Project of PLA;the Beijing Natural Science Foundation(7242279);the Beijing Nova Pro-gram(20230484283);the Beijing Municipal Science & Technology Commission(Z221100007422130);the Open Project of State Key Laboratory of Trauma and Chemical Poisoning(SKLO202401)
- DOI：10.1186/s40779-025-00596-1
  中图分类号：
- 收稿：2024-07-13，
  
  录用：2025-01-26，
  
  网络首发：2025-03-03，
  
  纸质出版：2025-11
- Accepted：
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Xin-Ling Li, Yu-Qing Zhao, Li Miao, 等. Strategies for promoting neurovascularization in bone regeneration[J]. Military Medical Research, 2025,12(11):1747-1781.

Xin-Ling Li, Yu-Qing Zhao, Li Miao, et al. Strategies for promoting neurovascularization in bone regeneration[J]. Military Medical Research, 2025, 12(11): 1747-1781.
Xin-Ling Li, Yu-Qing Zhao, Li Miao, 等. Strategies for promoting neurovascularization in bone regeneration[J]. Military Medical Research, 2025,12(11):1747-1781. DOI： 10.1186/s40779-025-00596-1.

Xin-Ling Li, Yu-Qing Zhao, Li Miao, et al. Strategies for promoting neurovascularization in bone regeneration[J]. Military Medical Research, 2025, 12(11): 1747-1781. DOI： 10.1186/s40779-025-00596-1.

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Strategies for promoting neurovascularization in bone regeneration

Strategies for promoting neurovascularization in bone regeneration

DOI：10.1186/s40779-025-00596-1