Tumor dormancy and relapse:understanding the molecular mechanisms of cancer recurrence

Muhammad Tufail; Can-Hua Jiang; Ning Li

doi:10.1186/s40779-025-00595-2

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Tumor dormancy and relapse:understanding the molecular mechanisms of cancer recurrence

REVIEW | Updated：2025-12-13

- Tumor dormancy and relapse:understanding the molecular mechanisms of cancer recurrence
- Tumor dormancy and relapse:understanding the molecular mechanisms of cancer recurrence
- “在对抗癌症的战斗中，了解肿瘤休眠是至关重要的。这篇综述深入探讨了休眠的细胞、血管生成和免疫方面，阐明了目前针对休眠细胞的治疗策略，包括联合疗法和免疫疗法，这些疗法可以预防癌症复发并改善患者的预后。”
- Military Medical Research 2025年12卷第9期页码：1456-1491
- Affiliations：
  
  1.Department of Oral and Maxillofacial Surgery, Center of Stomatology, Xiangya Hospital, Central South University, Changsha 410008, China
  2.Institute of Oral Precancerous Lesions, Central South University, Changsha 410008, China
  3.Research Center of Oral and Maxillofacial Tumor, Xiangya Hospital, Central South University, Changsha 410008, China
  4.National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China
- Author bio：
  
  * Ning Li liningoms@csu.edu.cn
- Funds：
  
  the National Natural Sciences Foundation of China(82170974);the Central South University Research Program of Advanced Interdisciplinary Studies(2023QYJC038)
- DOI：10.1186/s40779-025-00595-2
  中图分类号：
- 收稿：2024-07-10，
  
  录用：2025-01-26，
  
  网络首发：2025-02-11，
  
  纸质出版：2025-09
- Accepted：
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Muhammad Tufail, Can-Hua Jiang, Ning Li. Tumor dormancy and relapse:understanding the molecular mechanisms of cancer recurrence[J]. Military Medical Research, 2025,12(9):1456-1491.

Muhammad Tufail, Can-Hua Jiang, Ning Li. Tumor dormancy and relapse:understanding the molecular mechanisms of cancer recurrence[J]. Military Medical Research, 2025, 12(9): 1456-1491.
Muhammad Tufail, Can-Hua Jiang, Ning Li. Tumor dormancy and relapse:understanding the molecular mechanisms of cancer recurrence[J]. Military Medical Research, 2025,12(9):1456-1491. DOI： 10.1186/s40779-025-00595-2.

Muhammad Tufail, Can-Hua Jiang, Ning Li. Tumor dormancy and relapse:understanding the molecular mechanisms of cancer recurrence[J]. Military Medical Research, 2025, 12(9): 1456-1491. DOI： 10.1186/s40779-025-00595-2.

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Tumor dormancy and relapse:understanding the molecular mechanisms of cancer recurrence

Tumor dormancy and relapse:understanding the molecular mechanisms of cancer recurrence

DOI：10.1186/s40779-025-00595-2