<italic style="font-style: italic">In situ</italic> genetic engineering of host T-cells based on acellular scaffold strategy: a big but also small step for solid tumor immunotherapy

Shu-Yan Han; Zi-Xuan Zhao; Jun Wu

doi:10.1186/s40779-024-00517-8

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In situ genetic engineering of host T-cells based on acellular scaffold strategy: a big but also small step for solid tumor immunotherapy

COMMENTARY | Updated：2025-12-13

- In situ genetic engineering of host T-cells based on acellular scaffold strategy: a big but also small step for solid tumor immunotherapy
- In situ genetic engineering of host T-cells based on acellular scaffold strategy: a big but also small step for solid tumor immunotherapy
- “在xxx领域，xx专家取得了重大的研究进展。通过建立xx体系/探索xx主题/验证xx猜想，xx为解决xx问题提供了解决方案/为xx研究开辟了新方向/为xx体系的构建奠定了基础。”
- MMR 2025年12卷第4期页码：636-638
- Affiliations：
  
  1.Bioscience and Biomedical Engineering Thrust, the Hong Kong University of Science and Technology (Guangzhou), Guangzhou 511400, China
  2.Department of Nephrology, Center of Kidney and Urology, the Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen 518107, Guangdong, China
  3.Division of Life Science, the Hong Kong University of Science and Technology, Hong Kong 999077, China
- Author bio：
  
  *junwuhkust@ust.hk
- Funds：
  
  the National Natural Science Foundation of China(52173150);the Guangzhou Science and Technology Program City-University Joint Funding Project(2023A03J0001);the Postdoctoral Fellowship Program of CPSF(GZC20233297)
- DOI：10.1186/s40779-024-00517-8
  中图分类号：
- 纸质出版：2025-04
- Accepted：
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In situ genetic engineering of host T-cells based on acellular scaffold strategy: a big but also small step for solid tumor immunotherapy[J]. MMR, 2025,12(4):636-638.

Cite this article as: Han SY, Zhao ZX, Wu J. In situ genetic engineering of host T-cells based on acellular scaffold strategy: a big but also small step for solid tumor immunotherapy. Mil Med Res. 2024;11(1):12.
In situ genetic engineering of host T-cells based on acellular scaffold strategy: a big but also small step for solid tumor immunotherapy[J]. MMR, 2025,12(4):636-638. DOI： 10.1186/s40779-024-00517-8.

Cite this article as: Han SY, Zhao ZX, Wu J. In situ genetic engineering of host T-cells based on acellular scaffold strategy: a big but also small step for solid tumor immunotherapy. Mil Med Res. 2024;11(1):12. DOI： 10.1186/s40779-024-00517-8.

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In situ genetic engineering of host T-cells based on acellular scaffold strategy: a big but also small step for solid tumor immunotherapy

In situ genetic engineering of host T-cells based on acellular scaffold strategy: a big but also small step for solid tumor immunotherapy

DOI：10.1186/s40779-024-00517-8