Antimicrobial resistance crisis: could artificial intelligence be the solution?

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Antimicrobial resistance crisis: could artificial intelligence be the solution?

REVIEW | Updated：2025-02-24

- Antimicrobial resistance crisis: could artificial intelligence be the solution?
- Antimicrobial resistance crisis: could artificial intelligence be the solution?
- “面对抗微生物耐药性对全球公共卫生的威胁，世界卫生组织（世界卫生组织）发布了一份需要开发新抗生素的病原体优先名单。然而，新抗生素的发现和引入既费时又昂贵。在此背景下，人工智能（AI）已迅速应用于药物开发，显著提高了发现新抗生素的效率。本文总结了抗菌药物开发和利用领域的最新进展，包括小分子、抗菌肽、噬菌体疗法、精油，以及耐药机制预测和抗生素管理。”
- MMR 2025年12卷第1期页码：72-95
- Affiliations：
  
  1.Department of Immunology and Pathogen Biology, School of Basic Medical Sciences, Hangzhou Normal University, Key Laboratory of Aging and Cancer Biology of Zhejiang Province, Key Laboratory of Inflammation and Immunoregulation of Hangzhou, Hangzhou Normal University, Hangzhou 311121, China
  2.National Key Discipline of Pediatrics Key Laboratory of Major Diseases in Children Ministry of Education, Laboratory of Dermatology, Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing 100045, China
  3.Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN 55905, USA
  4.Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA
  5.Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
  6.Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK
  7.Institute of Antibiotics, Huashan Hospital, Fudan University, Key Laboratory of Clinical Pharmacology of Antibiotics, National Health Commission of the People’s Republic of China, National Clinical Research Centre for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China
- Author bio：
  
  *christoph.tang@path.ox.ac.uk;
  xiaofenliu@fudan.edu.cn
- Funds：
  
  the National Natural Science Foundation of China(32300157);the Shanghai Municipal Science and Technology Commission(19411964900);the Major Research and Development Project of Innovative Drugs, Ministry of Science and Technology of China(2017ZX09304005);the Wellcome Trust
- DOI：10.1186/s40779-024-00510-1
  中图分类号：
- 纸质出版：2025-01
- Accepted：
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Antimicrobial resistance crisis: could artificial intelligence be the solution?[J]. MMR, 2025,12(1):72-95.

Cite this article as: Liu GY, Yu D, Fan MM, Zhang X, Jin ZY, Tang C, et al. Antimicrobial resistance crisis: could artificial intelligence be the solution?. Mil Med Res. 2024;11(1):7.
Antimicrobial resistance crisis: could artificial intelligence be the solution?[J]. MMR, 2025,12(1):72-95. DOI： 10.1186/s40779-024-00510-1.

Cite this article as: Liu GY, Yu D, Fan MM, Zhang X, Jin ZY, Tang C, et al. Antimicrobial resistance crisis: could artificial intelligence be the solution?. Mil Med Res. 2024;11(1):7. DOI： 10.1186/s40779-024-00510-1.

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