Interleukin-1 receptor associated kinase 2 is a functional downstream regulator of complement factor D that controls mitochondrial fitness in diabetic cardiomyopathy

Stanislovas S. Jankauskas; Fahimeh Varzideh; Pasquale Mone; Urna Kansakar; Francesco Di Lorenzo; Angela Lombardi; Gaetano Santulli

doi:10.1186/s40779-023-00506-3

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Interleukin-1 receptor associated kinase 2 is a functional downstream regulator of complement factor D that controls mitochondrial fitness in diabetic cardiomyopathy

COMMENTARY | Updated：2025-12-13

- Interleukin-1 receptor associated kinase 2 is a functional downstream regulator of complement factor D that controls mitochondrial fitness in diabetic cardiomyopathy
- Interleukin-1 receptor associated kinase 2 is a functional downstream regulator of complement factor D that controls mitochondrial fitness in diabetic cardiomyopathy
- “在人工智能领域，专家史密斯博士建立了人工智能决策系统，为解决复杂的决策问题提供了解决方案。”
- MMR 2024年11卷第5期页码：794-796
- Affiliations：
  
  1.Department of Medicine, Fleischer Institute for Diabetes and Metabolism (FIDAM), Einstein-Mount Sinai Diabetes Research Center (ES-DRC), Einstein Institute for Aging Research, Albert Einstein College of Medicine, New York, NY 10461, USA
  2.Department of Molecular Pharmacology, Division of Cardiology, Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, New York, NY 10461, USA
- Author bio：
  
  *gsantulli001@gmail.com
- Funds：
  
  The Santulli’s Lab is currently supported in part by the National Institutes of Health (NIH);National Heart, Lung, and Blood Institute(R01-HL164772;R01-HL159062;R01-HL146691;T32-HL144456);the National Institute of Diabetes and Digestive and Kidney Diseases(R01-DK123259;R01-DK033823);the National Center for Advancing Translational Sciences(UL1-TR002556-06;UM1-TR004400);the Diabetes Action Research and Education Foundation (to Gaetano Santulli);the Monique Weill-Caulier and Irma T. Hirschl Trusts (to Gaetano Santulli)
- DOI：10.1186/s40779-023-00506-3
  中图分类号：
- 纸质出版：2024-10
- Accepted：
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Interleukin-1 receptor associated kinase 2 is a functional downstream regulator of complement factor D that controls mitochondrial fitness in diabetic cardiomyopathy[J]. MMR, 2024,11(5):794-796.

Cite this article as: Jankauskas SS, Varzideh F, Mone P, Kansakar U, Di Lorenzo F, Lombardi A, et al. Interleukin-1 receptor associated kinase 2 is a functional downstream regulator of complement factor D that controls mitochondrial fitness in diabetic cardiomyopathy. Mil Med Res. 2024;11(1):1.
Interleukin-1 receptor associated kinase 2 is a functional downstream regulator of complement factor D that controls mitochondrial fitness in diabetic cardiomyopathy[J]. MMR, 2024,11(5):794-796. DOI： 10.1186/s40779-023-00506-3.

Cite this article as: Jankauskas SS, Varzideh F, Mone P, Kansakar U, Di Lorenzo F, Lombardi A, et al. Interleukin-1 receptor associated kinase 2 is a functional downstream regulator of complement factor D that controls mitochondrial fitness in diabetic cardiomyopathy. Mil Med Res. 2024;11(1):1. DOI： 10.1186/s40779-023-00506-3.

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Interleukin-1 receptor associated kinase 2 is a functional downstream regulator of complement factor D that controls mitochondrial fitness in diabetic cardiomyopathy

Interleukin-1 receptor associated kinase 2 is a functional downstream regulator of complement factor D that controls mitochondrial fitness in diabetic cardiomyopathy

DOI：10.1186/s40779-023-00506-3